Results 1 to 10 of about 25,295 (178)

Evaluating the effect of equine tetanus antitoxin on mortality rates of dogs affected by tetanus [PDF]

open access: yesVeterinary Evidence
PICO Question In dogs with tetanus, does administering the equine tetanus antitoxin compared to not administering the antitoxin reduce mortality rates?   Clinical bottom line Category of research Treatment.
Berry Wong
doaj   +2 more sources

Modeling sRNA-Regulated Plasmid Maintenance. [PDF]

open access: yesPLoS ONE, 2017
We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid.
Chen Chris Gong, Stefan Klumpp
doaj   +1 more source

Establishment of a Novel Oral Murine Model of Ricin Intoxication and Efficacy Assessment of Ovine Ricin Antitoxins

open access: yesToxins, 2020
Ricin, produced from the castor beans of Ricinus communis, is a cytotoxin that exerts its action by inactivating ribosomes and causing cell death. Accidental (e.g., ingestion of castor beans) and/or intentional (e.g., suicide) exposure to ricin through ...
Sarah J. Whitfield   +6 more
doaj   +1 more source

Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures

open access: yesToxins, 2020
Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures.
Reut Falach   +14 more
doaj   +1 more source

IN VITRO ESTIMATION OF POTENCY OF SOME CLOSTRIDIAL TOXOIDS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2005
The efficacy of the toxin binding inhibition test (ToBi) as an in vitro testing of potency for multicomponent clostridial vaccine was compared with the currently used toxin neutralization test (TN).
M.M. FAYEZ, A.A. EL-MENISY, A.Z. HUSSEIN
doaj   +1 more source

Investigation of the Frequency of Foodborne Botulism in Patients Referred to Loghman Hospital in Tehran City, Iran, From 2008 to 2019 [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
Background: Foodborne botulism is a fatal paralytic illness caused mainly by the neurotoxin produced by an anaerobic bacterium called Clostridium botulinum. In this study, the frequency of foodborne botulism in patients referred to a hospital in Iran has
Mohammad Mehdi Soltan Dallal   +7 more
doaj   +1 more source

Medical Countermeasures against Ricin Intoxication

open access: yesToxins, 2023
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species.
Christine Rasetti-Escargueil   +1 more
doaj   +1 more source

Purification and characterization of alkaline soda-bleach stable protease from Bacillus sp. APP-07 isolated from Laundromat soil

open access: yesJournal of Genetic Engineering and Biotechnology, 2018
The detergent-compatible alkaline protease was produced from the bacterial strain Bacillus sp. APP-07 isolated from Laundromat soil of Solapur, Maharashtra, India.
I.K. Shaikh, P.P. Dixit, T.M. Shaikh
doaj   +1 more source

Production, Characterisation and Testing of an Ovine Antitoxin against Ricin; Efficacy, Potency and Mechanisms of Action

open access: yesToxins, 2017
Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and ...
Sarah J. C. Whitfield   +8 more
doaj   +1 more source

A case of asymmetric cranial nerve palsy due to iatrogenic botulism [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2021
Introduction:Botulism is a rare but lethal disease and atypical clinical presentations of this disease are difficult to diagnose. We report a case of iatrogenic botulism who presented withasymmetric cranial nerve involvement.Case report:An eighteen year ...
Muhammad Akbar Baig, Joshua Nogar
doaj   +1 more source

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