Results 21 to 30 of about 25,295 (178)
mBio, 2020 Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is arguably one of the most widespread transposon families.
Gipsi Lima-Mendez +6 more
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Bio-Protocol, 2023 Toxin–antitoxin (TA) systems are widespread bacterial immune systems that confer protection against various environmental stresses. TA systems have been classified into eight types (I–VIII) based on the nature and mechanism of action of the antitoxin ...
Parthasarathy Manikandan +2 more
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An oxygen-sensitive toxin–antitoxin system
Nature Communications, 2016 Classical toxin–antitoxin systems in bacteria are based on silencing of a toxin by an antitoxin that, when inactivated, releases the toxin, resulting in a change in metabolism. Here, the authors characterize an oxygen-sensitive toxin–antitoxin system and
Oriol Marimon +13 more
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Toxins, 2020 Botulinum neurotoxin serotype E (BoNT/E) is one of the major causes of human botulism, which is a life-threatening disease caused by flaccid paralysis of muscles. After receptor-mediated toxin internalization into motor neurons, the translocation domain (
Kwok-Ho Lam +3 more
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JAMA: The Journal of the American Medical Association, 1899 In a lecture delivered by Dr. T. Clifford Allbutt, regius professor of physics in Cambridge University, England, before the Johns Hopkins University in October, 1898, occur these words 1 : "The study of origins, then, is not only the new method of modern criticism, of modern history, of modern anthropology, of our reading of the evolution of the ...
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Chaperone addiction of toxin–antitoxin systems
Nature Communications, 2016 Some bacterial toxin-antitoxin systems consist of a labile antitoxin that inhibits a toxin, and a chaperone that stabilizes the antitoxin. Here, Bordes et al.
Patricia Bordes +8 more
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Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin
Emerging Infectious Diseases, 2016 Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin +5 more
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