Results 41 to 50 of about 33,062 (220)
Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin
Emerging Infectious Diseases, 2016 Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin +5 more
doaj +1 more source
JAMA: The Journal of the American Medical Association, 1899 In a lecture delivered by Dr. T. Clifford Allbutt, regius professor of physics in Cambridge University, England, before the Johns Hopkins University in October, 1898, occur these words 1 : "The study of origins, then, is not only the new method of modern criticism, of modern history, of modern anthropology, of our reading of the evolution of the ...
openaire +2 more sources
Antibodies and Vaccines against Botulinum Toxins: Available Measures and Novel Approaches
Toxins, 2019 Botulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium Clostridium botulinum. As one of the most poisonous toxins known and a potential bioterrosism agent, BoNT is characterized by a complex mode of action comprising ...
Christine Rasetti-Escargueil +1 more
doaj +1 more source
Toxins, 2018 Ricin, a highly lethal toxin derived from the seeds of Ricinus communis (castor beans) is considered a potential biological threat agent due to its high availability, ease of production, and to the lack of any approved medical countermeasure against ...
Reut Falach +11 more
doaj +1 more source
Regulation of toxin-antitoxin systems by proteolysis. [PDF]
, 2013 Toxin-antitoxin systems are widely distributed among many bacterial species, including human pathogens. Regulation of type II TA system functions, where both components are proteins, relies on proteolysis.
Brzozowska, Iwona +1 more
core +1 more source
ANTITOXIN AND DIPHTHERIA. [PDF]
JAMA: The Journal of the American Medical Association, 1897 At a meeting held here about a year ago I read a paper entitled "Diphtheria," in which the subject was treated in its entirety and some reference was made to the use of antitoxin serum. The paper which I present tonight deals chiefly with antitoxin and some reference is made to diphtheria as seems to be proper or relevant to the subject.
openaire +2 more sources
Diverse genetic contexts of HicA toxin domains propose a role in anti-phage defense
mBioToxin–antitoxin (TA) modules are prevalent in prokaryotic genomes, often in substantial numbers. For instance, the Mycobacterium tuberculosis genome alone harbors close to 100 TA modules, half of which belong to a singular type.
Kenn Gerdes
doaj +1 more source
Advanced Science, EarlyView.Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source