Results 21 to 30 of about 408,181 (229)

Immunogenicity, safety, and reactogenicity of combined reduced-antigen-content diphtheria-tetanus-acellular pertussis vaccine administered as a booster vaccine dose in healthy Russian participants: a phase III, open-label study

Human Vaccines & Immunotherapeutics, 2021
As vaccine-induced immunity and protection following natural pertussis infection wane over time, adults and adolescents may develop pertussis and become transmitters to unprotected infants.
Asmik Asatryan, Nadia Meyer, Michael Scherbakov, Victor Romanenko, Irina Osipova, Anna Galustyan, Olga Shamsheva, Tatiana Latysheva, Tatyana Myasnikova, Nathalie Baudson, Monique Dodet, Stebin Xavier, Lauriane Harrington, Anastasia Kuznetsova, Laura Campora, Peter Van den Steen   +15 more
doaj   +1 more source

Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection

BMC Infectious Diseases, 2021
Background The prevalent resurgence of pertussis has recently become a critical public health problem worldwide. To understand pertussis pathogenesis and the host response to both the pathogen and vaccines, a suitable pertussis animal model, particularly
Wenwen Jiang, Chen Wei, Dachao Mou, Weilun Zuo, Jiangli Liang, Xiao Ma, Lichan Wang, Na Gao, Qin Gu, Peng Luo, Yan Ma, Jingyan Li, Shuyuan Liu, Li Shi, Mingbo Sun   +14 more
doaj   +1 more source

The Aftermath of Flood Crises- Diphtheria Outbreak in Sindh [PDF]

Liaquat National Journal of Primary Care, 2023
The recent floods in Pakistan have not only resulted in greater than 1290 deaths and 12500 flood-related injuries but also thousands of cases of communicable and non-communicable diseases [1].
Syed Bilal Hashmi, Laraib Malik
doaj   +1 more source

Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards [PDF]

Osong Public Health and Research Perspectives, 2018
Objectives Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo toxin neutralization assay.
Chan Woong Choi, Jae Hoon Moon, Jae Ok Kim, Si Hyung Yoo, Hyeon Guk Kim, Jung-Hwan Kim, Tae Jun Park, Sung Soon Kim   +7 more
doaj   +1 more source

Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

Emerging Infectious Diseases, 2016
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin, Ana Avila-Alonso, Milagros González-Rivera, Eduardo Tamayo, Jose María Eiros, Raquel Almansa   +5 more
doaj   +1 more source

Vaccinations in pregnancy: An update for a changing time

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Maternal immunization is one of the most effective public health interventions to reduce infectious morbidity and mortality in pregnant women, fetuses, and newborns. Despite robust evidence supporting vaccine safety and effectiveness in pregnancy, global uptake has declined following the COVID‐19 pandemic, contributing to resurgent outbreaks ...
Wendy Hodge, Méabh Bhuinneáin, Gelila Goba, Marisa Labovsky, Eliana Amaral, Asma Khalil, David Lissauer, Hema Divakar, Fionnuala M. McAuliffe, Deborah Money, Dharmintra Pasupathy, on behalf of the FIGO Committee on Infections During Pregnancy   +11 more
wiley   +1 more source

Vaccination for girls and women across the life course: Evidence‐based recommendations for clinical practice and policy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Vaccination across the life course is a cornerstone of preventive health care for girls and women. Although WHO recommends completion of essential vaccines by adolescence, global coverage remains suboptimal. Vaccine‐preventable diseases—including HPV‐related cancers, vaginal, vulvar, anal, oropharyngeal, influenza, pertussis, hepatitis B ...
Hema Divakar, Fionnuala M. McAuliffe, Gelila Goba, Chiara Benedetto, Méabh N. Bhuinneáin, Suvarna Khadilkar, Marisa Labovsky, Michael Abou‐Dakn, Eytan R. Barnea, Agnaldo Lopes da Silva‐Filho, Elizabete Argale, Andrea Genazzani, Diana Ramos, Dharmintra Pasupathy   +13 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Diphtheria Toxoid Particles as Q Fever Vaccine

, 2023
There is an unmet need for a stable and nonreactogenic vaccine against the bioterrorism agent, Coxiella burnetii, causing Q fever. Here a safe, effective, and non-reactogenic Q fever vaccine is developed by employing self-assembled particles (CPs ...
Marsh, I, Plain, K, Rehm, BHA, Chen, S, Graves, SR, Stenos, J, Sam, G, Westman, ME   +7 more
core   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래, Wook-Jin Park, Sang-Nae Cho, Yeong-Jae Seok, Yeon-Kyung Yoon, Ruchirkumar Pansuriya, Ji-Sun Park, Youngmi Kim, Ravi Ganapathy   +8 more
core   +1 more source