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Tetanus is caused by the tetanus neurotoxin (TeNT) and is one of the most dreaded diseases especially in the developing countries. The current vaccine against tetanus is based on an inactivated tetanus toxin, which is effective but has many drawbacks. In
Rui Yu +9 more
doaj +1 more source
Neonatal tetanus in St. Mary’s Hospital Lacor: A case report
Umbilical stump sepsis in a nonpassively immunized neonate poses a high risk to neonatal tetanus. Management of neonatal tetanus is still a great challenge in resource‐limited settings where some health facilities lack tetanus toxoid containing vaccines,
Ronald Okidi +2 more
doaj +1 more source
Background Maternal neonatal tetanus is a substantial public health problem in many developing countries. In 2017, nearly, 30,848 newborns died of neonatal tetanus; thus, high immunization coverage remains a necessity. This study aims to assess knowledge
Azza Mehanna +2 more
doaj +1 more source
Background Globally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015 ...
Muhabaw Shumye Mihret +2 more
doaj +1 more source
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou +10 more
wiley +1 more source
Antibody kinetics against tetanus toxoid before and after primary vaccination of foals
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich +2 more
wiley +1 more source
The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid
The aim of this study was to investigate an antibody response to tetanus toxoid in iron-deficient piglets. Ten piglets were not given any iron preparation until the age of 21 days.
M. Svoboda +5 more
doaj +1 more source
Childhood Tetanus Complicating Snakebite: A Case Report From a Semi-urban Area, Northwestern Nigeria
For more than 6 decades, snakebite has been recognized as an important global public health problem. Such bites can be complicated by mortality and various forms of morbidities including tetanus.
Sanni Abiola Usman +4 more
doaj +1 more source
ABSTRACT Aim To provide an update paper on evidence of adverse events of concern following immunization (AEFI) with pertussis vaccines, focusing primarily on acellular (aP) vaccines. Methods Evidence was synthesised from epidemiological studies, systematic reviews over recent decades, expert interpretations in reviews from relevant research teams and ...
Lennart Nilsson, Jann Storsaeter
wiley +1 more source

