Results 31 to 40 of about 18,468 (169)

The monoclonal antibody 26 raised against tetanus toxoid also recognizes tetanus toxin and b2-glycoprotein I – its binding properties in vitro and potential applications [PDF]

Journal of the Serbian Chemical Society, 2009
A murine monoclonal IgG1 antibody, marked as MAb26, specific for tetanus toxoid has been immunochemically characterized. By performing enzyme-linked immunosorbent assays (ELISAs) and western blot analyses, it was demonstrated that MAb26 reacted with ...
ALEKSANDRA B. INIĆ-KANADA, MARIJANA M. STOJANOVIĆ, IRENA P. ŽIVKOVIĆ, VLADIMIR Ž. PETRUŠIĆ, LJILJANA A. DIMITRIJEVIĆ   +4 more
doaj  

Comparative Immunogenicity of the Tetanus Toxoid and Recombinant Tetanus Vaccines in Mice, Rats, and Cynomolgus Monkeys

Toxins, 2016
Tetanus is caused by the tetanus neurotoxin (TeNT) and is one of the most dreaded diseases especially in the developing countries. The current vaccine against tetanus is based on an inactivated tetanus toxin, which is effective but has many drawbacks. In
Rui Yu, Ting Fang, Shuling Liu, Xiaohong Song, Changming Yu, Jianmin Li, Ling Fu, Lihua Hou, Junjie Xu, Wei Chen   +9 more
doaj   +1 more source

Knowledge and health beliefs of reproductive-age women in Alexandria about tetanus toxoid immunization

Journal of the Egyptian Public Health Association, 2020
Background Maternal neonatal tetanus is a substantial public health problem in many developing countries. In 2017, nearly, 30,848 newborns died of neonatal tetanus; thus, high immunization coverage remains a necessity. This study aims to assess knowledge
Azza Mehanna, Mervat H. Ali, Ibrahim Kharboush   +2 more
doaj   +1 more source

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Antibody kinetics against tetanus toxoid before and after primary vaccination of foals

Equine Veterinary Journal, EarlyView.
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich, Monica Venner, Bettina Wagner   +2 more
wiley   +1 more source

The role of timely initiation of antenatal care on protective dose tetanus toxoid immunization: the case of northern Ethiopia post natal mothers

BMC Pregnancy and Childbirth, 2018
Background Globally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015 ...
Muhabaw Shumye Mihret, Miteku Andualem Limenih, Temesgen Worku Gudayu   +2 more
doaj   +1 more source

Neonatal tetanus in St. Mary’s Hospital Lacor: A case report

Clinical Case Reports, 2020
Umbilical stump sepsis in a nonpassively immunized neonate poses a high risk to neonatal tetanus. Management of neonatal tetanus is still a great challenge in resource‐limited settings where some health facilities lack tetanus toxoid containing vaccines,
Ronald Okidi, Vanusa Da Consolação Sambo, Jacob Eyul   +2 more
doaj   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

The absence of iron deficiency effect on the humoral immune response of piglets to tetanus toxoid

Veterinární Medicína, 2007
The aim of this study was to investigate an antibody response to tetanus toxoid in iron-deficient piglets. Ten piglets were not given any iron preparation until the age of 21 days.
M. Svoboda, K. Nechvatalova, J. Krejci, J. Drabek, R. Ficek, M. Faldyna   +5 more
doaj   +1 more source