Results 71 to 80 of about 188,459 (209)

Precise control of SCRaMbLE in synthetic haploid and diploid yeast

open access: yesNature Communications, 2018
Compatibility between host cells and heterologous pathways is a challenge for constructing organisms with high productivity or gain of function. Designer yeast cells incorporating the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated ...
Bin Jia   +18 more
semanticscholar   +1 more source

Haploid Selection in “Diploid” Organisms

open access: yesAnnual Review of Ecology, Evolution and Systematics, 2019
Evolutionary rates and strength of selection differ markedly between haploid and diploid genomes. Any genes expressed in a haploid state will be directly exposed to selection, whereas alleles in a diploid state may be partially or fully masked by a ...
S. Immler
semanticscholar   +1 more source

Heterozygous diploid and interspecies SCRaMbLEing

open access: yesNature Communications, 2018
SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) is a genome restructuring technique that can be used in synthetic genomes such as that of Sc2.0, the synthetic yeast genome, which contains hundreds to thousands of
Michael J Shen   +13 more
semanticscholar   +1 more source

Studies on Colchicine Induced Chromosome Doubling for Enhancement of Quality Traits in Ornamental Plants

open access: yesPlants, 2019
Polyploidy has the utmost importance in horticulture for the development of new ornamental varieties with desirable morphological traits referring to plant size and vigor, leaf thickness, larger flowers with thicker petals, intense color of leaves and ...
Ayesha Manzoor   +4 more
doaj   +1 more source

Genetic effects of combining ability studies for quantitative traits in intra- and interspecific crosses of diploid cotton (G. arboreum and G. herbaceum)

open access: yesElectronic Journal of Plant Breeding, 2017
Forty-five intra- and interspecific diploid or desi cotton hybrids (G. arboreum x G. herbaceum) derived from half diallel mating design, by involving ten diverse parents of G. herbaceum and G.
Rakesh Choudhary   +4 more
doaj   +1 more source

A graph-based approach to diploid genome assembly

open access: yesBioinform., 2018
Motivation Constructing high‐quality haplotype‐resolved de novo assemblies of diploid genomes is important for revealing the full extent of structural variation and its role in health and disease.
S. Garg   +5 more
semanticscholar   +1 more source

Evolution of haploid-diploid life cycles when haploid and diploid fitnesses are not equal. [PDF]

open access: yesEvolution; international journal of organic evolution, 2017
Many organisms spend a significant portion of their life cycle as haploids and as diploids (a haploid-diploid life cycle). However, the evolutionary processes that could maintain this sort of life cycle are unclear. Most previous models of ploidy evolution have assumed that the fitness effects of new mutations are equal in haploids and homozygous ...
Scott, Michael, Rescan, Marie
openaire   +4 more sources

Assembly and diploid architecture of an individual human genome via single-molecule technologies

open access: yesNature Methods, 2015
We present the first comprehensive analysis of a diploid human genome that combines single-molecule sequencing with single-molecule genome maps. Our hybrid assembly markedly improves upon the contiguity observed from traditional shotgun sequencing ...
Matthew Pendleton   +27 more
semanticscholar   +1 more source

Application of metabolomics approach to investigate the flavor substance differences between triploid and diploid oysters (Crassostrea angulata)

open access: yesFrontiers in Marine Science
Oysters, particularly Portuguese oyster (Crassostrea angulata), are highly valued for their nutritional and flavor qualities, making them important in global aquaculture.
Duo Chen   +6 more
doaj   +1 more source

Induction of tetraploidy in Juncus effusus by colchicine

open access: yesBiologia Plantarum, 2010
Tetraploidy was induced in vitro in mat rush (Juncus effusus L.) cultivar Nonglin-4 by exposure to colchicine (0, 50, 100 and 500 mg dm-3) for 6, 12 and 24 h. Flow cytometric analysis was used to confirm the ploidy level.
L. Xu   +7 more
doaj   +1 more source

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