Results 1 to 10 of about 39,841 (160)
Colchicine and the heart [PDF]
European Heart Journal, 2021 Abstract Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for decades for the prevention of acute inflammatory flares in gout and familial Mediterranean fever. In recent years, clinical trials have demonstrated its potential in a range of cardiovascular (CV) conditions.
Stefan Nidorf +2 more
exaly +4 more sources
Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L [PDF]
BMC Plant BiologyPurpose Stimulating flowering ability is the main purpose of commercial development of ornamental plants. Colchicine could contribute to improve flowering and related physiological processes; however its potential mode on marigold (Calendula officinalis)
Makka A. Hassan +3 more
doaj +2 more sources
Colchicine has Dose‐Dependent Therapeutic Effects in a LPS‐Induced Experimental Endotoxemia Model [PDF]
Pharmacology Research & PerspectivesColchicine is an ancient medication that has long been used for anti‐inflammatory properties. Because of unfavorable and toxic consequences of colchicine, selecting an appropriate dose is critical. The effects of three different doses (0.5, 1 or 5 mg/kg)
Meliksah Demir +5 more
doaj +2 more sources
Frontiers in Pharmacology, 2021 Background: The beneficial effects of colchicine on cardiovascular disease have been widely reported in recent studies. Previous research demonstrated that colchicine has a certain protective effect on ischemic myocardium and has the potential to treat ...
Yuanjun Tang +8 more
doaj +1 more source
Effect of Colchicine on Secondary Acute Lung Injury in an Experimental Sepsis Model in Rats
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2023 Introduction: An irregular systemic inflammatory response in sepsis can induce acute lung injury (ALI), which is characterized by the exaggerated inflammation of the lung tissue.
Mehmet CEYLAN +4 more
doaj +1 more source
Colchicine for pericarditis [PDF]
American Journal of Health-System Pharmacy, 2014 We read with great interest the recent article by Eun and Smith,[1][1] which provides a commendable review on the safety and efficacy of colchicine for treating acute and recurrent pericarditis.
Lovely, Chhabra, David H, Spodick
openaire +6 more sources
Radioimmunoassay of colchicine [PDF]
Biochemical Journal, 1975 Antibodies to cholchicine were raised in rabbits after injection of N-desacetylthiocolchicine conjugated to bovine serum albumin. Antisera diluted 1:100 bound 50% of 1.6ng of [3H]colchicine. Cross-reaction of the antisera with colchicine derivatives and other drugs was measured and a radioimmunoassay of colchicine in biological fluids was proposed.
C, Boudene, F, Duprey, C, Bohuon
openaire +2 more sources
Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Frontiers in Pharmacology, 2020 Colchicine is a plant alkaloid that is widely used as a therapeutic agent. It is widely accepted that colchicine reduces the production of inflammatory mediators mainly by altering cytoskeleton dynamics due to its microtubule polymerization inhibitory ...
Carola Muñoz-Montesino +11 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundThis study investigated the effect of colchicine use on the risks of heart disease (HD), pericarditis, endocarditis, myocarditis, cardiomyopathy, cardiac arrhythmia, and cardiac failure in patients having interstitial lung disease (ILD) with ...
Jun-Jun Yeh +11 more
doaj +1 more source
International Journal of Cardiology: Heart & Vasculature, 2023 Background: Colchicine has anti-inflammatory properties, but its utility in improving cardiovascular outcomes has been disputed. Here, we study the impact of colchicine on cardiovascular outcomes in patients with gout with and without coronary artery ...
Muhammad U. Siddiqui +5 more
doaj +1 more source