Results 41 to 50 of about 16,654 (233)

Successfully Treated Severe Colchicine Intoxication in an Adolescent

Türk Yoğun Bakim Derneği Dergisi, 2022
The contain is extracted from the autumn crocus plant, colchicine that an anti-inflammatory drug. The use of colchicine impairs mobilization and activation of neutrophil and supporting treating from some rheumatological diseases especially in childhood ...
Hatice Feray Arı, Berna Kırhan, Murat Arı   +2 more
doaj   +1 more source

Low-dose colchicine prevents sympathetic denervation after myocardial ischemia-reperfusion: a new potential protective mechanism

Future Science OA, 2021
Purpose: To evaluate the impact of colchicine on sympathetic denervation after acute myocardial infarction (AMI). Materials & methods: Ischemia/Reperfusion was induced in C57BL/6J male mice.
Fabien Huet, Jérémy Fauconnier, Marion Legall, Pierre Sicard, Catherine Lozza, Alain Lacampagne, François Roubille   +6 more
doaj   +1 more source

Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient

Kidney Research and Clinical Practice, 2013
Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh, Ji Young Joung, Hyemin Jeong, Dongmo Je, Yoon Young Cho, Hye Ryoun Jang, Wooseong Huh   +6 more
doaj   +1 more source

Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. [PDF]

PLoS ONE, 2016
Tubulin isotypes are found to play an important role in regulating microtubule dynamics. The isotype composition is also thought to contribute in the development of drug resistance as tubulin isotypes show differential binding affinities for various anti-
Bajarang Vasant Kumbhar, Anubhaw Borogaon, Dulal Panda, Ambarish Kunwar   +3 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Rhabdomyolysis associated with concomitant use of colchicine and statins in the real world: identifying the likelihood of drug–drug interactions through the FDA adverse event reporting system

Frontiers in Pharmacology
BackgroundCurrently, there remains substantial controversy in research regarding whether the concomitant use of colchicine and statins increases the occurrence of rhabdomyolysis, warranting further substantiation.ObjectiveThis study aimed to identify the
Sha Zhang, Ming-Ming Yan, Hui Zhao, Xiao-Yan Qiu, Deqiu Zhu   +4 more
doaj   +1 more source

Effects of colchicine use on ischemic and hemorrhagic stroke risk in diabetic patients with and without gout

Scientific Reports, 2022
This study aimed to determine the effect of colchicine use on the risk of stroke among patients with diabetes mellitus (DM). We retrospectively enrolled patients with DM between 2000 and 2013 from the Longitudinal Health Insurance Database and divided ...
Jun-Jun Yeh, I-Ling Kuo, Hei-Tung Yip, Min-Yuan Hsueh, Chung-Y. Hsu, Chia-Hung Kao   +5 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

Effect of Treatment with Colchicine after Acute Coronary Syndrome on Major Cardiovascular Events: A Systematic Review and Meta-Analysis of Clinical Trials

Cardiovascular Therapeutics, 2022
Aim. Colchicine as an anti-inflammatory drug might be effective in the treatment of atherosclerosis, an inflammatory-based condition. The aim of this systematic review and meta-analysis was to evaluate the impact of colchicine on acute coronary syndrome (
Erfan Razavi, Akam Ramezani, Asma Kazemi, Armin Attar   +3 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source