Results 21 to 30 of about 50,572 (275)
Effect of Colchicine on Secondary Acute Lung Injury in an Experimental Sepsis Model in Rats
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2023 Introduction: An irregular systemic inflammatory response in sepsis can induce acute lung injury (ALI), which is characterized by the exaggerated inflammation of the lung tissue.
Mehmet CEYLAN +4 more
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Radioimmunoassay of colchicine [PDF]
Biochemical Journal, 1975 Antibodies to cholchicine were raised in rabbits after injection of N-desacetylthiocolchicine conjugated to bovine serum albumin. Antisera diluted 1:100 bound 50% of 1.6ng of [3H]colchicine. Cross-reaction of the antisera with colchicine derivatives and other drugs was measured and a radioimmunoassay of colchicine in biological fluids was proposed.
C, Boudene, F, Duprey, C, Bohuon
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Frontiers in Cardiovascular Medicine, 2022 BackgroundThis study investigated the effect of colchicine use on the risks of heart disease (HD), pericarditis, endocarditis, myocarditis, cardiomyopathy, cardiac arrhythmia, and cardiac failure in patients having interstitial lung disease (ILD) with ...
Jun-Jun Yeh +11 more
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Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Frontiers in Pharmacology, 2020 Colchicine is a plant alkaloid that is widely used as a therapeutic agent. It is widely accepted that colchicine reduces the production of inflammatory mediators mainly by altering cytoskeleton dynamics due to its microtubule polymerization inhibitory ...
Carola Muñoz-Montesino +11 more
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Colchicine treatment in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: A multicenter study in Spain [PDF]
, 2021 Objective: To evaluate the efficacy of colchicine therapy in pediatric patients with PFAPA syndrome who present with an incomplete response to the standard treatment or with frequent episodes (an interval of less than 14 days between two disease flares).
Olbrich, Peter +10 more
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International Journal of Cardiology: Heart & Vasculature, 2023 Background: Colchicine has anti-inflammatory properties, but its utility in improving cardiovascular outcomes has been disputed. Here, we study the impact of colchicine on cardiovascular outcomes in patients with gout with and without coronary artery ...
Muhammad U. Siddiqui +5 more
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Colchicine reduces atherosclerotic plaque vulnerability in rabbits
Atherosclerosis Plus, 2021 Background and aims: The anti-inflammatory agent colchicine is gaining interest as a treatment for coronary artery disease. However, the effects of colchicine in atherosclerotic animal models are mostly unknown. This study aimed to evaluate colchicine in
François Roubille +12 more
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Frontiers in Pharmacology, 2019 Objectives: A previous study suggested that colchicine may cause leukopenia and increase the risk of infection, such as pneumonia. Thus, we investigated the potential relationship between colchicine use and risk of developing pneumonia.Methods: Data were
Tsung-Lin Tsai +8 more
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Arthritis & Rheumatism, 1991 The purpose of this discussion is to examine these two concerns, the efficacy and safety of colchicine, in the context of this controversy.
L W, Moreland, G V, Ball
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Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation
Frontiers in Immunology, 2022 BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications ...
Ulrike Meyer-Lindemann +23 more
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