Results 21 to 30 of about 16,654 (233)

Colchicine reduces atherosclerotic plaque vulnerability in rabbits

open access: yesAtherosclerosis Plus, 2021
Background and aims: The anti-inflammatory agent colchicine is gaining interest as a treatment for coronary artery disease. However, the effects of colchicine in atherosclerotic animal models are mostly unknown. This study aimed to evaluate colchicine in
François Roubille   +12 more
doaj   +1 more source

High colchicine doses are more effective in COVID-19 outpatients than nirmatrelvir/ritonavir, remdesivir, and molnupiravir [PDF]

open access: yesPharmacia
Colchicine has an excellent basis for being effective against COVID-19 due to its anti-inflammatory, immunomodulatory, and cardioprotective effects, as well as its role in preventing microvascular thrombosis.
Vanyo Mitev   +11 more
doaj   +3 more sources

Destabilising microtubule polymerization regulates chondrocyte dedifferentiation and inflammation via nuclear factor kappa b and β-catenin pathway

open access: yesBangladesh Journal of Pharmacology, 2023
The role of cell morphological changes in colchicine-inhibited tubulin polymerization of rabbit articular chondrocytes and their involvement in dedifferentiation were investigated.
Yohan Han   +3 more
doaj   +1 more source

COLCHICINE [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1876
n ...
openaire   +2 more sources

THE EFFECT OF COLCHICINE ON THE PIGMENTATION OF THE ENAMEL SURFACE IN RAT INCISORS [PDF]

open access: yes, 1984
The effect of colchicine and lumicolchicine on the secretion of an iron containing pigment vesicle onto the enamel surface in the rat maxillary incisors has been studied histologically and by line scan analysis of the iron with an X-ray microanalyzer ...
Keiko, HASHIMOTO
core   +1 more source

Anticancer effects of clinically acceptable colchicine concentrations on human gastric cancer cell lines

open access: yesKaohsiung Journal of Medical Sciences, 2016
Colchicine is a very cheap microtubule destabilizer. Because microtubules are an ideal target for anticancer drugs, the purpose of this study was to investigate whether clinically acceptable colchicine concentrations have anticancer effects on gastric ...
Zu-Yau Lin   +3 more
doaj   +1 more source

Pengaruh Manipulasi Ploidi Terhadap Efektivitas Pertumbuhan dan Hasil Tanaman Labu Kuning (Cucurbita moschene Dutchene)

open access: yesRekayasa, 2023
Pumpkin (Cucurbita moschene Duthene) is plant sources of food that has high nutrition content. Increasing the productivity of pumpkin can be done through programs, which is the ploidy manipulation technique, the technique using a mutagen, namely ...
Reza Prakoso Dwi Julianto   +2 more
doaj   +1 more source

In silico study of colchicine resistance molecular mechanisms caused by tubulin structural polymorphism.

open access: yesPLoS ONE, 2019
Starting from 1972, colchicine is known as the most useful drug for prevention of familial Mediterranean fever attacks. However, some patients do not respond to colchicine treatment, even taken in high doses.
Harutyun Sahakyan   +4 more
doaj   +1 more source

Production of colchicine by using plant cell culture [PDF]

open access: yes, 2005
Plant cell and tissue culture is an established alternative to the harvest and extraction of whole plant material for the production of valuable secondary metabolites.
Aroud, Gamal
core   +2 more sources

Case Report: Colchicine Toxicokinetic Analysis in a Poisoned Child Requiring Extracorporeal Life Support

open access: yesFrontiers in Pediatrics, 2021
Colchicine poisoning is associated with a poor prognosis, especially when leading to shock and multi-organ failure, and management is limited to supportive care, including multiple-dose activated charcoal.
Maria Pérez Marín   +9 more
doaj   +1 more source

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