Results 11 to 20 of about 57,858 (265)
Current Pharmaceutical Design, 2018 Background: Colchicine is an ancient drug. Many uses have been reported in medical books and reports through the centuries. Currently the understanding of its mechanism of action has opened new horizons to its use. Objective: This article aims to discuss the use of colchicine in various neurosurgical conditions.
Drosos, E. +2 more
openaire +4 more sources
Journal of Pure and Applied Microbiology, 2017 The objective of this study was to identify and study the effect of colchicine treatment on the growth and enzyme production of Pycnoporus coccineus KKUPN1.
W. Sutthisa1 , Sanoamuang2,3
doaj +2 more sources
Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient
Kidney Research and Clinical Practice, 2013 Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh +6 more
doaj +2 more sources
Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity
ToxinsColchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang +5 more
doaj +2 more sources
Colchicine Overdose in a Suicidal Attempt [PDF]
International Journal of Medical Toxicology and Forensic Medicine, 2019 Colchicine overdose is uncommon; however, it can cause serious adverse effects and even death. Colchicine inhibits microtubule polymerization, causing mitotic spindle disruption.
Fatemeh Eghbali +6 more
doaj +3 more sources
Colchicine for pericarditis [PDF]
American Journal of Health-System Pharmacy, 2014 We read with great interest the recent article by Eun and Smith,[1][1] which provides a commendable review on the safety and efficacy of colchicine for treating acute and recurrent pericarditis.
Lovely, Chhabra, David H, Spodick
openaire +6 more sources
Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo [PDF]
, 2004 In gene therapy, a clinically relevant therapeutic effect requires long-term expression of the desired gene at a level sufficient to correct or at least alleviate the underlying gene defect.
Pfützner, Wolfgang, Vogel, Jonathan C.
core +2 more sources
Radioimmunoassay of colchicine [PDF]
Biochemical Journal, 1975 Antibodies to cholchicine were raised in rabbits after injection of N-desacetylthiocolchicine conjugated to bovine serum albumin. Antisera diluted 1:100 bound 50% of 1.6ng of [3H]colchicine. Cross-reaction of the antisera with colchicine derivatives and other drugs was measured and a radioimmunoassay of colchicine in biological fluids was proposed.
C, Boudene, F, Duprey, C, Bohuon
openaire +2 more sources
Arthritis & Rheumatism, 1991 The purpose of this discussion is to examine these two concerns, the efficacy and safety of colchicine, in the context of this controversy.
L W, Moreland, G V, Ball
openaire +2 more sources
An open-label continuation trial of tocilizumab for familial Mediterranean fever with colchicine ineffective or intolerance [PDF]
, 2020 Background:Colchicine is the first-line treatment for familial Mediterranean fever (FMF), but secondary amyloidosis resulting from persistent inflammation is a concern in patients with colchicine-resistant or colchicine-intolerant FMF.
Fukushima, Chizu +15 more
core +1 more source