Results 11 to 20 of about 16,654 (233)
Current Pharmaceutical Design, 2018 Background: Colchicine is an ancient drug. Many uses have been reported in medical books and reports through the centuries. Currently the understanding of its mechanism of action has opened new horizons to its use. Objective: This article aims to discuss the use of colchicine in various neurosurgical conditions.
Drosos, E. +2 more
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Journal of Pure and Applied Microbiology, 2017 The objective of this study was to identify and study the effect of colchicine treatment on the growth and enzyme production of Pycnoporus coccineus KKUPN1.
W. Sutthisa1 , Sanoamuang2,3
doaj +2 more sources
Biorhizome: A Biosynthetic Platform for Colchicine Biomanufacturing [PDF]
Frontiers in Plant Science, 2017 Colchicine is one of the oldest plant-based medicines used to treat gout and one of the most important alkaloid-based antimitotic drugs with anticancer potential, which is commercially extracted from Gloriosa superba.
Ganapathy Sivakumar +2 more
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Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity
ToxinsColchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang +5 more
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MedicinaBackground and Objectives: Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease characterized by recurrent febrile attacks and serosal inflammation.
Mehmet Nur Kaya +4 more
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Colchicine Overdose in a Suicidal Attempt [PDF]
International Journal of Medical Toxicology and Forensic Medicine, 2019 Colchicine overdose is uncommon; however, it can cause serious adverse effects and even death. Colchicine inhibits microtubule polymerization, causing mitotic spindle disruption.
Fatemeh Eghbali +6 more
doaj +3 more sources
Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo [PDF]
, 2004 In gene therapy, a clinically relevant therapeutic effect requires long-term expression of the desired gene at a level sufficient to correct or at least alleviate the underlying gene defect.
Pfützner, Wolfgang, Vogel, Jonathan C.
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Colchicine treatment in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: A multicenter study in Spain [PDF]
, 2021 Objective: To evaluate the efficacy of colchicine therapy in pediatric patients with PFAPA syndrome who present with an incomplete response to the standard treatment or with frequent episodes (an interval of less than 14 days between two disease flares).
Olbrich, Peter +10 more
core +1 more source
An open-label continuation trial of tocilizumab for familial Mediterranean fever with colchicine ineffective or intolerance [PDF]
, 2020 Background:Colchicine is the first-line treatment for familial Mediterranean fever (FMF), but secondary amyloidosis resulting from persistent inflammation is a concern in patients with colchicine-resistant or colchicine-intolerant FMF.
Fukushima, Chizu +15 more
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Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation
Frontiers in Immunology, 2022 BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications ...
Ulrike Meyer-Lindemann +23 more
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