Results 11 to 20 of about 39,902 (221)

The Association Between Usage of Colchicine and Pneumonia: A Nationwide, Population-Based Cohort Study

open access: yesFrontiers in Pharmacology, 2019
Objectives: A previous study suggested that colchicine may cause leukopenia and increase the risk of infection, such as pneumonia. Thus, we investigated the potential relationship between colchicine use and risk of developing pneumonia.Methods: Data were
Tsung-Lin Tsai   +8 more
doaj   +1 more source

Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation

open access: yesFrontiers in Immunology, 2022
BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications ...
Ulrike Meyer-Lindemann   +23 more
doaj   +1 more source

Colchicine and gout [PDF]

open access: yesArthritis & Rheumatism, 1991
The purpose of this discussion is to examine these two concerns, the efficacy and safety of colchicine, in the context of this controversy.
L W, Moreland, G V, Ball
openaire   +2 more sources

Colchicine reduces atherosclerotic plaque vulnerability in rabbits

open access: yesAtherosclerosis Plus, 2021
Background and aims: The anti-inflammatory agent colchicine is gaining interest as a treatment for coronary artery disease. However, the effects of colchicine in atherosclerotic animal models are mostly unknown. This study aimed to evaluate colchicine in
François Roubille   +12 more
doaj   +1 more source

High colchicine doses are more effective in COVID-19 outpatients than nirmatrelvir/ritonavir, remdesivir, and molnupiravir [PDF]

open access: yesPharmacia
Colchicine has an excellent basis for being effective against COVID-19 due to its anti-inflammatory, immunomodulatory, and cardioprotective effects, as well as its role in preventing microvascular thrombosis.
Vanyo Mitev   +11 more
doaj   +3 more sources

Colchicine in Neurosurgery

open access: yesCurrent Pharmaceutical Design, 2018
Background: Colchicine is an ancient drug. Many uses have been reported in medical books and reports through the centuries. Currently the understanding of its mechanism of action has opened new horizons to its use. Objective: This article aims to discuss the use of colchicine in various neurosurgical conditions.
Drosos, E.   +2 more
openaire   +3 more sources

Pengaruh Manipulasi Ploidi Terhadap Efektivitas Pertumbuhan dan Hasil Tanaman Labu Kuning (Cucurbita moschene Dutchene)

open access: yesRekayasa, 2023
Pumpkin (Cucurbita moschene Duthene) is plant sources of food that has high nutrition content. Increasing the productivity of pumpkin can be done through programs, which is the ploidy manipulation technique, the technique using a mutagen, namely ...
Reza Prakoso Dwi Julianto   +2 more
doaj   +1 more source

COLCHICINE [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1876
n ...
openaire   +2 more sources

Anticancer effects of clinically acceptable colchicine concentrations on human gastric cancer cell lines

open access: yesKaohsiung Journal of Medical Sciences, 2016
Colchicine is a very cheap microtubule destabilizer. Because microtubules are an ideal target for anticancer drugs, the purpose of this study was to investigate whether clinically acceptable colchicine concentrations have anticancer effects on gastric ...
Zu-Yau Lin   +3 more
doaj   +1 more source

Destabilising microtubule polymerization regulates chondrocyte dedifferentiation and inflammation via nuclear factor kappa b and β-catenin pathway

open access: yesBangladesh Journal of Pharmacology, 2023
The role of cell morphological changes in colchicine-inhibited tubulin polymerization of rabbit articular chondrocytes and their involvement in dedifferentiation were investigated.
Yohan Han   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy