Results 11 to 20 of about 50,572 (275)

Colchicine in Neurosurgery

open access: yesCurrent Pharmaceutical Design, 2018
Background: Colchicine is an ancient drug. Many uses have been reported in medical books and reports through the centuries. Currently the understanding of its mechanism of action has opened new horizons to its use. Objective: This article aims to discuss the use of colchicine in various neurosurgical conditions.
Drosos, E.   +2 more
openaire   +4 more sources

Colchicine for pericarditis [PDF]

open access: yesAmerican Journal of Health-System Pharmacy, 2014
We read with great interest the recent article by Eun and Smith,[1][1] which provides a commendable review on the safety and efficacy of colchicine for treating acute and recurrent pericarditis.
Lovely, Chhabra, David H, Spodick
core   +7 more sources

Identification of Pycnoporus coccineus KKUPN1 and Effect of Colchicine Treatment on Growth and Enzyme Production

open access: yesJournal of Pure and Applied Microbiology, 2017
The objective of this study was to identify and study the effect of colchicine treatment on the growth and enzyme production of Pycnoporus coccineus KKUPN1.
W. Sutthisa1 , Sanoamuang2,3
doaj   +2 more sources

Biorhizome: A Biosynthetic Platform for Colchicine Biomanufacturing [PDF]

open access: yesFrontiers in Plant Science, 2017
Colchicine is one of the oldest plant-based medicines used to treat gout and one of the most important alkaloid-based antimitotic drugs with anticancer potential, which is commercially extracted from Gloriosa superba.
Ganapathy Sivakumar   +2 more
doaj   +2 more sources

Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L [PDF]

open access: yesBMC Plant Biology
Purpose Stimulating flowering ability is the main purpose of commercial development of ornamental plants. Colchicine could contribute to improve flowering and related physiological processes; however its potential mode on marigold (Calendula officinalis)
Makka A. Hassan   +3 more
doaj   +2 more sources

Colchicine has Dose‐Dependent Therapeutic Effects in a LPS‐Induced Experimental Endotoxemia Model [PDF]

open access: yesPharmacology Research & Perspectives
Colchicine is an ancient medication that has long been used for anti‐inflammatory properties. Because of unfavorable and toxic consequences of colchicine, selecting an appropriate dose is critical. The effects of three different doses (0.5, 1 or 5 mg/kg)
Meliksah Demir   +5 more
doaj   +2 more sources

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity

open access: yesToxins
Colchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang   +5 more
doaj   +2 more sources

Colchicine Overdose in a Suicidal Attempt [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2019
Colchicine overdose is uncommon; however, it can cause serious adverse effects and even death. Colchicine inhibits microtubule polymerization, causing mitotic spindle disruption.
Fatemeh Eghbali   +6 more
doaj   +3 more sources

Colchicine and the heart [PDF]

open access: yesEuropean Heart Journal, 2021
Abstract Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for decades for the prevention of acute inflammatory flares in gout and familial Mediterranean fever. In recent years, clinical trials have demonstrated its potential in a range of cardiovascular (CV) conditions.
Massimo Imazio, Mark Nidorf
openaire   +3 more sources

Network Pharmacology-Based Investigation and Experimental Exploration of the Antiapoptotic Mechanism of Colchicine on Myocardial Ischemia Reperfusion Injury

open access: yesFrontiers in Pharmacology, 2021
Background: The beneficial effects of colchicine on cardiovascular disease have been widely reported in recent studies. Previous research demonstrated that colchicine has a certain protective effect on ischemic myocardium and has the potential to treat ...
Yuanjun Tang   +8 more
doaj   +1 more source

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