Results 31 to 40 of about 39,902 (221)

The etiology and autopsy findings in Colchicine intoxication-related deaths

open access: yesMedicine Science, 2016
Colchicine is a drug which has a very narrow therapeutic range. This drug has been commonly used for Familial Mediterranean Fever (FMF), Behcet’s disease, gout arthritis and acute pseudo gout attacks.
Servet Birgin Iritas   +7 more
doaj   +1 more source

Transcriptome analysis reveals plant response to colchicine treatment during on chromosome doubling

open access: yesScientific Reports, 2017
Colchicine was commonly used to artificially double chromosomes while the transcriptome changes in colchicine treated plants has rarely been characterized.
Kai Zhou   +4 more
doaj   +1 more source

Low-dose colchicine prevents sympathetic denervation after myocardial ischemia-reperfusion: a new potential protective mechanism

open access: yesFuture Science OA, 2021
Purpose: To evaluate the impact of colchicine on sympathetic denervation after acute myocardial infarction (AMI). Materials & methods: Ischemia/Reperfusion was induced in C57BL/6J male mice.
Fabien Huet   +6 more
doaj   +1 more source

Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient

open access: yesKidney Research and Clinical Practice, 2013
Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh   +6 more
doaj   +1 more source

Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. [PDF]

open access: yesPLoS ONE, 2016
Tubulin isotypes are found to play an important role in regulating microtubule dynamics. The isotype composition is also thought to contribute in the development of drug resistance as tubulin isotypes show differential binding affinities for various anti-
Bajarang Vasant Kumbhar   +3 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

Rhabdomyolysis associated with concomitant use of colchicine and statins in the real world: identifying the likelihood of drug–drug interactions through the FDA adverse event reporting system

open access: yesFrontiers in Pharmacology
BackgroundCurrently, there remains substantial controversy in research regarding whether the concomitant use of colchicine and statins increases the occurrence of rhabdomyolysis, warranting further substantiation.ObjectiveThis study aimed to identify the
Sha Zhang   +4 more
doaj   +1 more source

Effects of colchicine use on ischemic and hemorrhagic stroke risk in diabetic patients with and without gout

open access: yesScientific Reports, 2022
This study aimed to determine the effect of colchicine use on the risk of stroke among patients with diabetes mellitus (DM). We retrospectively enrolled patients with DM between 2000 and 2013 from the Longitudinal Health Insurance Database and divided ...
Jun-Jun Yeh   +5 more
doaj   +1 more source

Colchicine in overdose [PDF]

open access: yesBritish Journal of General Practice, 2016
Would colleagues please be aware of the devastating consequences of a significant colchicine …
openaire   +2 more sources

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

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