Results 31 to 40 of about 16,654 (233)

Comparison of Different Pharmaceutical Preparations of Colchicine in Children with Familial Mediterranean Fever: Is Colchicine Opocalcium a Good Alternative?

, 2021
Background: Colchicine is an anti-inflammatory agent used for preventing familial Mediterranean fever (FMF) attacks and amyloidosis.
Selçuk Yüksel, Unsal, Erbil, Serkan Türkuçar, Makay, BALAHAN, Acari, Ceyhun, Balahan Makay, Yukser, Selcuk, Yuksel, Selcuk, Ceyhun Acari, Gülçin Otar Yener, Erbil Ünsal, Turkucar, Serkan, Yener, Gulcin Otar, Hatice Adıgüzel Dundar, Dundar, Hatice Adiguzel   +14 more
core   +1 more source

Clinically acceptable colchicine concentrations have potential for the palliative treatment of human cholangiocarcinoma

Kaohsiung Journal of Medical Sciences, 2015
Microtubules are an ideal target for anticancer drugs because of their essential role in mitosis. Colchicine is a microtubule destabilizer. Whether the clinically acceptable colchicine concentrations had anticancer effects on human cholangiocarcinoma ...
Chun-Chieh Wu, Zu-Yau Lin, Chao-Hung Kuoc, Wan-Long Chuang   +3 more
doaj   +1 more source

Comparison of the efficacy and safety of tocilizumab for colchicine-resistant or colchicine-intolerant familial Mediterranean fever: study protocol for an investigator-initiated, multicenter, randomized, double-blind, placebo-controlled trial [PDF]

, 2018
Background: Familial Mediterranean fever (FMF) is an inherited disorder caused by a number of mutations of the Mediterranean fever (MEFV) gene, coding a protein named pyrin that acts as a major regulatory component of the inflammasome.The first-line ...
Fukushima, Chizu, Kawakami, Atsushi, Chizu Fukushima, Arinaga, Kumiko, Yamamoto, Hiroshi, Junya Miyamoto, Sato, Shuntaro, Koga, Tomohiro, Kawazoe, Yurika, Junya Miyamoto (6164702), Atsushi Kawakami (398370), Chizu Fukushima (6164714), Yurika Kawazoe, Hagimori, Naoko, Tomohiro Koga, Naoko Hagimori, Kumiko Arinaga (6164711), Kumiko Arinaga, Hiroshi Yamamoto, Naoko Hagimori (6164705), Tomohiro Koga (398369), Shuntaro Sato (4025585), Hiroshi Yamamoto (28534), Shuntaro Sato, Atsushi Kawakami, Yurika Kawazoe (6164708), Miyamoto, Junya   +26 more
core   +1 more source

The etiology and autopsy findings in Colchicine intoxication-related deaths

Medicine Science, 2016
Colchicine is a drug which has a very narrow therapeutic range. This drug has been commonly used for Familial Mediterranean Fever (FMF), Behcet’s disease, gout arthritis and acute pseudo gout attacks.
Servet Birgin Iritas, Ahmet Hakan Dinc, Baris Akduman, Bora Ozdemir, Ceylan Bal, Hacer Y. Teke, Mehtap Ozdemir, Bulent Degirmenci   +7 more
doaj   +1 more source

Reducing length of hospital stay with colchicine

Journal of Infection in Developing Countries, 2022
Introduction: Colchicine is an ancient agent with well-known anti-inflammatory effects and commonly used in treatment of hyperinflammatory conditions.
Özlem Karakaş, Abdulsamet Erden, Serdar Can Güven, Berkan Armağan, Enes Seyda Sahiner, Ali Can Kurtipek, Osman Inan, Emin Gemcioglu, İhsan Ateş, Ahmet Omma, Orhan Küçüksahin   +10 more
doaj   +1 more source

Colchicine in overdose [PDF]

British Journal of General Practice, 2017
We read with interest the letter from Lloyd warning of the danger of colchicine overdose1 and agree that this can have devastating consequences. However, the …
Edward, Roddy, Christian D, Mallen
openaire   +2 more sources

Biosynthesis of Colchicine [PDF]

Nature, 1960
OF several proposals1–4 concerning the biogenesis of the alkaloid colchicine (5; R 1 = R 2 = Me), only that of Wenkert4 involves the intervention of an intact tropolone ring prior to formation of ring B.
openaire   +2 more sources

Accompanying autoimmune diseases may have a role in colchicine resistance in adult familial mediterranean fever patients

Medicine Science
Colchicine is the primary treatment for familial Mediterranean fever (FMF); however, colchicine resistance poses a major challenge, affecting about 5–10% of patients.
Ozlem Kilic, Emre Tekgoz, Seda Colak, Mehmet Nur Kaya, Muhammet Cinar, Sedat Yilmaz   +5 more
doaj   +1 more source

Colchicine in overdose [PDF]

British Journal of General Practice, 2016
Would colleagues please be aware of the devastating consequences of a significant colchicine …
openaire   +2 more sources

Transcriptome analysis reveals plant response to colchicine treatment during on chromosome doubling

Scientific Reports, 2017
Colchicine was commonly used to artificially double chromosomes while the transcriptome changes in colchicine treated plants has rarely been characterized.
Kai Zhou, Paige Fleet, Eviatar Nevo, Xinquan Zhang, Genlou Sun   +4 more
doaj   +1 more source