Genome BiologyPloidy determination across the genome has been challenging for low-pass-WGS tumor-only samples. We present BACDAC, a method that calculates tumor ploidy down to 1.2X effective tumor coverage.
Sarah H. Johnson +9 more
doaj +1 more source
Origin and development of uniparental and polyploid blastomeres
iScienceSummary: Whole-genome (WG) abnormalities, such as uniparental diploidy and triploidy, cause fetal death. Occasionally, they coexist with biparental diploid cells in live births. Understanding the origin and early development of WG abnormal blastomeres is
Yan Zhao +12 more
doaj +1 more source
Hybrid incompatibilities are affected by dominance and dosage in the haplodiploid wasp Nasonia
Frontiers in Genetics, 2015 Study of genome incompatibilities in species hybrids is important for understanding the genetic basis of reproductive isolation and speciation. According to Haldane’s rulehybridization affects the heterogametic sex more than the homogametic sex.
Leo W Beukeboom +4 more
doaj +1 more source
DaapNLRSeek, prediction, and evolution of resistance genes in polyploid sugarcane genomes
iScienceSummary: Sugarcane (Saccharum spp. hybrids) is an important crop for sugar and biofuel production. However, pathogens cause significant yield losses.
Yiting Huang, Yingfeng Luo, Xiao Lin
doaj +1 more source
A Case with Neurofibromatosis and Chronic Myeloid Leukemia in Blastic Crisis Treated with Imatinib
Middle East Journal of Cancer, 2014 A 61-year-old female presented with complaints of fever, general weakness and hepatosplenomegaly. She had a history of nonfamilial peripheral neurofibromatosis diagnosed as von Recklinghausen's disease since 30 years previous. Physical examination was
Gamal Abdul Hamid, Iman Bin Harize
doaj
DNA PLOIDY AND NUCLEAR TEXTURE FEATURES OF THERETICULAR FORM OF ORAL LICHEN PLANUS
Zdravniški Vestnik, 2008 BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa with lowrisk of malignant transformation. At present there are no reliable tools to predict whichOLP will progress to cancer.
Matjaž Rode +3 more
doaj
PCR-based assay for mating type and diploidy in Chlamydomonas
BioTechniques, 2004 Ivan Zamora +2 more
doaj +1 more source
Correction: Zi et al. Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells. <i>Int. J. Mol. Sci.</i> 2015, <i>16</i>, 27228-27251. [PDF]
Int J Mol SciZi D +7 more
europepmc +1 more source