Results 41 to 50 of about 6,984 (172)
Mitotic recombination accelerates adaptation in the fungus Aspergillus nidulans. [PDF]
PLoS Genetics, 2007 Understanding the prevalence of sexual reproduction in eukaryotes is a hard problem. At least two aspects still defy a fully satisfactory explanation, the functional significance of genetic recombination and the great variation among taxa in the relative
Sijmen E Schoustra +3 more
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Journal of Cardiovascular Development and Disease, 2023 Adult hearts are characterized by inefficient regeneration after injury, thus, the features that support or prevent cardiomyocyte (CM) proliferation are important to clarify.
Hirofumi Watanabe +9 more
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New Phytologist, EarlyView.Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon +3 more
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G3: Genes, Genomes, Genetics, 2018 The haplodiploid system of sex determination of Hymenoptera acts as an exaptation for species to evolve novel forms of asexual reproduction including thelytoky (clonal offspring of the mother). During normal reproduction in Hymenoptera, three of the four
Benjamin P. Oldroyd +7 more
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Nonlinearities and Switch‐Like Behavior in Gene Expression: From Genetics to Biochemistry and Back
The FASEB Journal, Volume 40, Issue 16, 31 August 2026.Modest changes in transcription‐factor or chromatin‐regulator dosage can have disproportionate effects when gene‐regulatory systems operate near nonlinear thresholds. Sigmoidal input–output relationships, chromatin and cofactor recruitment, and changes in threshold position or response steepness provide molecular routes by which quantitative dosage ...
Reiner A. Veitia, James A. Birchler
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Current advances in haploid stem cells
Protein & Cell, 2019 Diploidy is the typical genomic mode in all mammals. Haploid stem cells are artificial cell lines experimentally derived in vitro in the form of different types of stem cells, which combine the characteristics of haploidy with a broad developmental ...
Tongtong Cui, Zhikun Li, Qi Zhou, Wei Li
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Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation [PDF]
Cell Stem Cell, 2017 Reporting in Nature Genetics, Patterson et al. (2017) show that adult mammalian hearts possess an innate capacity to regenerate, which depends on a small population of mononuclear diploid cardiomyocytes. These cells undergo karyokinesis and cytokinesis, raising the possibility that endogenous cardiac muscle cells can be stimulated to proliferate for ...
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Genomics is modifying our concepts of evolution in homosporous and heterosporous vascular plants
American Journal of Botany, Volume 113, Issue 8, August 2026.Abstract Across the tree of life, and particularly within land plants, there is a wide diversity and disparity of genome structure. The most well‐studied are angiosperms, comprising mostly small and dynamic genomes, with a history of ancient whole genome duplications.
Sylvia P. Kinosian
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Molecular and immunohistochemical characteristics of complete hydatidiform moles
Balkan Journal of Medical Genetics, 2017 Molar pregnancy is a gestational trophoblastic disease that belongs to the category of precancerous lesions. On the other end of the spectrum are gestational trophoblastic neoplasms such as invasive mole, choriocarcinoma, placental site trophoblastic ...
Kubelka-Sabit KB +6 more
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Prenatal Diagnosis, Volume 46, Issue 9, Page 1486-1493, August 2026.ABSTRACT Objective Prenatal genetic testing for imprinting disorders is rarely requested with the exception of Beckwith‐Wiedemann syndrome (BWS) which is associated with specific ultrasound findings (e.g., placental mesenchymal dysplasia, omphalocele). However, genetic testing for BWS is challenging as aberrant DNA methylation has to be addressed which
Melissa Connolly +10 more
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