The use of maize haploidy inducers as a tool in agricultural plant biotechnology [PDF]
Вавиловский журнал генетики и селекции, 2022 The discovery of the ability of some mutations to stimulate haploidy during hybridization made it possible to create one of the most promising and sought-after trends in the field of reproductive biology.
A. V. Ulyanov +2 more
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Haploidy-linked cell proliferation defects limit larval growth in zebrafish [PDF]
Open BiologyHaploid larvae in non-mammalian vertebrates are lethal, with characteristic organ growth retardation collectively called ‘haploid syndrome’. In contrast to mammals, whose haploid intolerance is attributed to imprinting misregulation, the cellular ...
Kan Yaguchi +8 more
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Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas [PDF]
Frontiers in OncologyThe mitogen-activated protein kinase (MAPK) signaling pathway plays roles in cell proliferation, differentiation, and apoptosis, all crucial for cellular transformation. It’s no surprise that MAPK alterations are prevalent in numerous tumors.
Ruze Tang +15 more
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Effect of Small Molecules on Blastocyst Development and Outgrowth Establishment of Bovine Haploid Parthenogenetic Embryos [PDF]
AnimalsHaploid embryos constitute a valuable model for genetic and epigenetic studies; however, their developmental competence is reduced compared with diploid counterparts.
Luis Aguila +8 more
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Gigas-Cell1 mediated in vivo haploid induction in Brassica napus: A step forward for hybrid development and crop improvement. [PDF]
Plant Biotechnol JPlant Biotechnology Journal, Volume 23, Issue 11, Page 4729-4731, November 2025.
Bakhsh MZM, Lei M, Zhang X, Ali A, Yi B.
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Imprinting as Basis for Complex Evolutionary Novelties in Eutherians [PDF]
BiologyThe epigenetic phenomenon of genomic imprinting is puzzling. While epigenetic modifications in general are widely known in most species, genomic imprinting in the animal kingdom is restricted to autosomes of therian mammals, mainly eutherians, and to a ...
Maximillian Schuff +3 more
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Androgenesis-Based Doubled Haploidy: Past, Present, and Future Perspectives
Frontiers in Plant Science, 2022 Androgenesis, which entails cell fate redirection within the microgametophyte, is employed widely for genetic gain in plant breeding programs. Moreover, androgenesis-responsive species provide tractable systems for studying cell cycle regulation, meiotic
Brett Hale +2 more
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Haploid Induction in Tomato (Solanum lycopersicum L.) via Gynogenesis [PDF]
Plants, 2022 The generation of new hybrid varieties of tomato (Solanum lycopersicum L.) is the most widely used breeding method for this species and requires at least seven self-fertilization cycles to generate stable parent lines. The development of doubled haploids
Ivan Maryn Marin-Montes +5 more
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Allelic Imbalance and Chromothripsis Lead to Diversity in Japanese Tumor Genomes With Whole-Genome Duplication. [PDF]
Cancer SciJapanese tumor genomes with whole‐genome duplication are diversified by allele imbalance and chromothripsis. These structural abnormalities are linked to a poor prognosis for cancer patients. ABSTRACT Whole‐genome analyses have revealed that large‐scale structural variations (SVs) such as whole‐genome duplication (WGD) occur early in the development of
Hatakeyama K +11 more
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Balanced DNA-to-cytoplasm ratio at the 2-cell stage is critical for mouse preimplantation development [PDF]
iScienceSummary: Among vertebrates, mammalian haploid embryos are highly prone to early developmental arrest for reasons that remain unclear. Using mouse preimplantation embryos with altered cell size and ploidy, we show that arrest primarily results from an ...
Tao Pan, Natsumi Taira, Miho Ohsugi
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