Haploidy-linked cell proliferation defects limit larval growth in zebrafish [PDF]
Open BiologyHaploid larvae in non-mammalian vertebrates are lethal, with characteristic organ growth retardation collectively called ‘haploid syndrome’. In contrast to mammals, whose haploid intolerance is attributed to imprinting misregulation, the cellular ...
Kan Yaguchi +8 more
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Овощи России, 2009 This article reviews means and a significance of homozygous lines production in tomato through haploid plant stage. The haploid plants can be originated both male and female cells of gametophyte.
N. A. Shmikova
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Effect of Small Molecules on Blastocyst Development and Outgrowth Establishment of Bovine Haploid Parthenogenetic Embryos [PDF]
AnimalsHaploid embryos constitute a valuable model for genetic and epigenetic studies; however, their developmental competence is reduced compared with diploid counterparts.
Luis Aguila +8 more
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Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas [PDF]
Frontiers in OncologyThe mitogen-activated protein kinase (MAPK) signaling pathway plays roles in cell proliferation, differentiation, and apoptosis, all crucial for cellular transformation. It’s no surprise that MAPK alterations are prevalent in numerous tumors.
Ruze Tang +15 more
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Imprinting as Basis for Complex Evolutionary Novelties in Eutherians [PDF]
BiologyThe epigenetic phenomenon of genomic imprinting is puzzling. While epigenetic modifications in general are widely known in most species, genomic imprinting in the animal kingdom is restricted to autosomes of therian mammals, mainly eutherians, and to a ...
Maximillian Schuff +3 more
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Balanced DNA-to-cytoplasm ratio at the 2-cell stage is critical for mouse preimplantation development [PDF]
iScienceSummary: Among vertebrates, mammalian haploid embryos are highly prone to early developmental arrest for reasons that remain unclear. Using mouse preimplantation embryos with altered cell size and ploidy, we show that arrest primarily results from an ...
Tao Pan, Natsumi Taira, Miho Ohsugi
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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells
Cell Reports, 2019 Summary: The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth ...
Maria Vega-Sendino +2 more
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Correction: Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas [PDF]
Frontiers in OncologyRuze Tang +15 more
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Haploidy in Drosophila Melanogaster [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1925 exaly +3 more sources
The use of maize haploidy inducers as a tool in agricultural plant biotechnology
Вавиловский журнал генетики и селекции, 2022 The discovery of the ability of some mutations to stimulate haploidy during hybridization made it possible to create one of the most promising and sought-after trends in the field of reproductive biology.
A. V. Ulyanov +2 more
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