Results 151 to 160 of about 678,745 (265)

Clinical and Safety Outcomes after Direct Anterior Total Hip Arthroplasty Compared with Conventional Approaches: A Systematic Review and Meta-Analysis. [PDF]

J Orthop Case Rep
Movva S, Koduru SK, Roop D, Pandiyarajan S, Edwards A, Choudhary AK.   +5 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Geospatial modelling for zoonotic disease hotspot identification within a One Health framework: a systematic review. [PDF]

One Health Outlook
Nyengere J, Mbewe W, Malalu L, Tholo H, Njala AL, Sembo T, Kumpolota SW, Mvula RL, Chisenga C, Kanyika-Mbewe C, Maluwa A, Eregno FE.   +11 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Management strategies and outcomes of basilar trunk aneurysms: a systematic review and meta-analysis. [PDF]

Langenbecks Arch Surg
Tian Z, Gu F, Li B, Meng J, Tao X, Jiang G, Fu R, Wang Z, You W.   +8 more
europepmc   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Saving the split: An umbrella review on therapeutic approaches for cracked tooth syndrome. [PDF]

J Conserv Dent Endod
Kaur S, Puzhankara L, Shenoy N, Kini KS, Singhal DK.   +4 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Incorporation of social medicine curriculum in academic and community health centres: a scoping review protocol. [PDF]

BMJ Open
Cydis M, Hudson E, Shipper AG, Lane A, Salzman M.   +4 more
europepmc   +1 more source

Direct search methods for influence maximization problems

The influence maximization problem seeks to maximize the spread of influence in network structures. This challenging optimization task remains unsolved due to its combinatorial nature and computational complexity. In this thesis, we propose two novel direct search methods, Neighbors Search (NS) and nonmonotone NS, which leverage the network structure ...
openaire   +1 more source