Results 131 to 140 of about 1,348,172 (305)
, 1988 The Rosenbrock Algorithm and the D. S. C. Algorithm, both direct search methods using orthogonal directions were implemented into a software. Values of the optimal parameters were determined and the performance was compared with each other and with the ...
San Luis, Jonas Marcos B
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Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Three-Layer Retrieval and Self-Evaluation Classification Method Based on FastText Algorithm
IEEE AccessPatent big data serves as a valuable scientific research source for technological innovation, enabling breakthroughs beyond existing knowledge and fostering disruptive ideas.
Yidan Li, Huanhuan Hong, Luhong Wen
doaj +1 more source
This chapter discusses various methods that have been used to estimate structural models of search and survival models. Most of the focus is on using available data, usually on unemployment spell lengths and accepted wage o¤ers, to estimate the ...
John Pepper, Steven Stern
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Integrative approaches to protein homology search
, 2005 Alam I. Integrative approaches to protein homology search. Bielefeld (Germany): Bielefeld University; 2005.Many methods have been developed to search for homologous members of a protein family in databases, and the reliability of results and conclusions ...
Alam, Intikhab
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
OPTIMIZATION BY DIRECT SEARCH IN MATRIX COMPUTATIONS [PDF]
, 1993 A direct search method attempts to maximize a function $f :{\bf R}^n \to {\bf R}$ using function values only. Many questions about the stability and accuracy of algorithms in matrix computations can be expressed in terms of the maximum value of some ...
Higham, Nicholas J., Higham, N J
core
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source