Results 151 to 160 of about 1,348,172 (305)

Methodologies][Artificial Intelligence]: Problem Solving, Control Methods,and Search General Terms: Algorithms,Theory

, 2008
the Search Space is presented. This modulation is developed as a mathematical method that can be implemented directly into existing evolutionary algorithms without writing special operators,changing the program loop etc.
Space Modification-reinterpretation, Keywords Search   +1 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Effectiveness of Guideline-Based Clinical Decision Support Systems: Protocol for a Systematic Review. [PDF]

JMIR Res Protoc
Aksu BN, Gashi B, Schiefenhövel F, Boeker M.   +3 more
europepmc   +1 more source

Finding local optima of high-dimensional functions using direct search methods

This paper focuses on a subclass of box-constrained, non-linear optimization problems. We are particularly concerned with settings where gradient information is unreliable, or too costly to calculate, and the function evaluations themselves are very ...
Glover, Fred, Hvattum, Lars Magnus
core  

Direct methods for power system transient stability analysis using BCU method

, 2013
textDirect methods are an alternative for power system transient stability analysis to avoid the enormous computational efforts of conventional time-domain method.
Dai, Chenxi, 1988-
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Preconception and first-trimester metformin for improving pregnancy outcomes in women with polycystic ovary syndrome. [PDF]

Cochrane Database Syst Rev
Devall AJ, Cheshire J, Periyathambi N, Garg A, Vigneswaran K, Melo P, Dhillon-Smith R, Coomarasamy A.   +7 more
europepmc   +1 more source

Incorporating minimum Frobenius norm models in direct search

, 2008
The goal of this paper is to show that the use of minimum Frobenius norm quadratic models can improve the performance of direct-search methods. The approach taken here is to maintain the structure of directional direct-search methods, organized around a ...
H. Rocha, L. N. Vicente, Vicente, Luís Nunes, A. L. Custódio, Custódio, Ana Luísa, Rocha, Humberto   +5 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Non-pharmacological interventions for anxiety and depression in Parkinson's disease. [PDF]

Cochrane Database Syst Rev
Li T, Shi J, Zheng Q, Xu JG, Zhang M, Ren Y, Zhang B, Li Z.   +7 more
europepmc   +1 more source