Results 51 to 60 of about 169,151 (235)
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Should Optimal Designers Worry About Consideration?
, 2015 Consideration set formation using non-compensatory screening rules is a vital component of real purchasing decisions with decades of experimental validation.
Long, Minhua, Morrow, W. Ross
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Use of At-Home Medical Tests Among Older US Adults: A Nationally Representative Survey
Inquiry: The Journal of Health Care Organization, Provision, and FinancingThe availability of direct-to-consumer, at-home medical tests has grown over the last decade, but it is unknown how frequently older adults purchase at-home tests, how they perceive such tests, and how interested they are in using at-home tests in the ...
Joshua B. Rager MD, MA, MS +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Recommendations for Chicago's Local Plan, Title I of the Workforce Investment Act of 1998 [PDF]
, 2000 This report provides a series of policy recommendations for local implementation of Title I of the Workforce Investment Act of 1998 (WIA) aimed at providing an integrated workforce development system that effectively serves both disadvantaged job-seekers
Whitney Smith
core
What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics. [PDF]
, 2018 The International Society of Psychiatric Genetics (ISPG) created a Residency Education Committee with the purpose of identifying key genetic knowledge that should be taught in psychiatric training programs.
Austin, Jehannine +11 more
core +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Voices in BioethicsPhoto ID 345549 © Jonathan Mulkey | Dreamstime.com Abstract Emerging DNA marketplace startups aim to empower individuals with greater control and potential profit-sharing over their genetic data, but they face ethical tensions in navigating ...
Alexis Walker
doaj +1 more source