Results 161 to 170 of about 10,263,018 (335)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Benefit!

open access: yes, 2000
Benefit featuring Danny O'Keefe, Eric Apoe and They, Axolotl, Todd Davis, Christine Gunn, Carla Torgenson.After WTOEvent PublicityDirect ...
Direct Action Network (DAN). Legal Defense Fund
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

If you believe in democracy vote with your feet and voice

open access: yes, 1999
Alternate title: Non-violent direct action, Nov 30. Alternate title: What are they trading?
Schuerholz, Dana
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Developing a Functional Framework to Teach and Learn Science at the Three Conceptual Levels of Understanding: An Action Research Approach

open access: yes, 2018
Many educators advocate that the teaching and learning of science should be done at three conceptual levels – the macroscopic, sub-microscopic and symbolic levels.
Wong, Yoke Ung, Koh, Bing Qin
core  

A direct action for GH in improvement of oocyte quality in poor-responder patients.

open access: yesReproduction, 2014
B. M. Weall   +4 more
semanticscholar   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

TRIMETAZIDINE AND MILDRONATE AS DIRECT ACTION Β2 - ADRENOSENSIBILIZERS (EXPERIMENTAL EVIDENCE)

open access: yesРоссийский кардиологический журнал, 2002
Trimetazidine and mildronate as direct action β2 - adrenosensibilizers (experimental evidence).
V. I. Tsirkin   +6 more
doaj  

Home - About - Disclaimer - Privacy