Results 181 to 190 of about 10,263,018 (335)

Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy. [PDF]

Oncol Res
Wang P, Chen YH, Zhan ZT, Zeng JX, Chen Y, Lin Y, Chen T, Zhou WJ.   +7 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Small but Mighty: Low Bio-Accessibility Preserves Polyphenols from Mini Purple Carrots for Direct Action Against Colon Cancer Cells. [PDF]

Antioxidants (Basel)
Hamdi A, Hasan Yusuf E, Rodríguez-Arcos R, Jiménez-Araujo A, Nowicka P, Guillén-Bejarano R, Jaramillo-Carmona S.   +6 more
europepmc   +1 more source

MetAP2 inhibition increases energy expenditure through direct action on brown adipocytes. [PDF]

J Biol Chem, 2019
Huang HJ, Holub C, Rolzin P, Bilakovics J, Fanjul A, Satomi Y, Plonowski A, Larson CJ, Farrell PJ.   +8 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Direct Action in British Environmentalism

, 2000
Direct action has become a key part of the strategy of the radical environmental movement since the early 1990s, used to address issues such as road building and car culture, genetically modified foods, consumerism and global finance institutions. It has

core   +1 more source

Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting. [PDF]

J Biomed Sci
Pan BS, Hsu CC, Wu HE, Chen YR, Zhou X, Wang SC, Li CY, Lin HK.   +7 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

If the WTO had existed during the anti-apartheid movement, Nelson Mandela would still be in jail because divestment and selective purchase laws would be ruled illegal by the WTO

, 1999
Alternate title: Non-violent direct action, Nov 30. Alternate title: What are they trading away?
Schuerholz, Dana
core  

Historical spatio-temporal data on North American radical environmental direct-action events. [PDF]

Data Brief
Almquist ZW, Bagozzi BE, Blinova D.
europepmc   +1 more source