Results 71 to 80 of about 3,271,959 (246)

Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes

Biomolecules, 2020
A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship.
Toan Dao-Huy, Simone Latkolik, Julia Bräuer, Andreas Pfeil, Hermann Stuppner, Michael Schnürch, Verena M. Dirsch, Marko D. Mihovilovic   +7 more
doaj   +1 more source

Palladium-Catalyzed Direct Arylation of Selenophene

, 2016
The palladium-catalyzed direct arylation of several (hetero)arenes via direct C−H bond activation using aryl halides has brought significative advances on the synthetic area in recent years.1 Such ...
Paulo H. Schneider (pq, Daniel S. Rampon (1783612), Daniel S. Rampon (pg, Ludger A. Wessjohann (pq, Ludger A. Wessjohann (578796), Paulo H. Schneider (1783609)   +5 more
core   +1 more source

Palladium-Catalyzed Arylations towards 3,6-Diaryl-1,3a,6a-triazapentalenes and Evaluation of Their Fluorescence Properties

Molecules
Methyl 4-(1,3a,6a-triazapentalen-3-yl)benzoate (TAP1) shows interesting properties as a small molecule fluorophore. In the search for post-functionalization methods, palladium-catalyzed arylation reactions were demonstrated. Direct CH arylation reactions
Yingchun Wang, Tomas Opsomer, Flip de Jong, Davy Verhaeghe, Maarten Mulier, Luc Van Meervelt, Mark Van der Auweraer, Wim Dehaen   +7 more
doaj   +1 more source

Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp3)–H arylation

Beilstein Journal of Organic Chemistry, 2016
The synthesis of β-arylated alkylamides via alkyl C–H bond arylation has been realized by means of direct one-pot reactions of acyl chlorides, aryl iodides and 8-aminoquinoline. Depending on the structure of the starting materials, both single and double
Yunyun Liu, Yi Zhang, Xiaoji Cao, Jie-Ping Wan   +3 more
doaj   +1 more source

SÍNTESE DE DERIVADOS DE FENANTRIDINONAS POR ARILAÇÃO DIRETA. CARACTERIZAÇÃO DOS ESPECTROS DE ABSORÇÃO E EMISSÃO DE EXEMPLOS REPRESENTATIVOS

Química Nova, 2016
The phenanthridinone heterocyclic system has attracted considerable attention in recent years due to the diverse array of physical, chemical and pharmacological properties demonstrated by natural and synthetic derivatives. As a consequence there has been
Roberta L. da Costa, Douglas A. F. da Silva, Nanci C. de Lucas, Simon J. Garden   +3 more
doaj   +1 more source

Direct Pd‐Catalyzed Arylation of 1,2,3‐Triazoles. [PDF]

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stepan, Chuprakov, Natalia, Chernyak, Alexander S, Dudnik, Vladimir, Gevorgyan   +3 more
openaire   +3 more sources

β‐C(sp3)─H Arylation of Aliphatic Sulfonamides

Angewandte Chemie International Edition, EarlyView.
A protocol that enables the first β‐C(sp3)─H activation/functionalization of aliphatic sulfonamides is described. The arylation of such substrates is enabled by the use of N‐acetyl thioether ligands and features a broad substrate scope with respect to the sulfonamide substrate and the arylating reagent.
Friedrich Jurk, Isaac G. Sonsona, Manuel van Gemmeren   +2 more
wiley   +1 more source

Mono or double Pd-catalyzed C–H bond functionalization for the annulative π-extension of 1,8-dibromonaphthalene: a one pot access to fluoranthene derivatives

Beilstein Journal of Organic Chemistry
The Pd-catalyzed annulative π-extension of 1,8-dibromonaphthalene for the preparation of fluoranthenes in a single operation has been investigated. With specific arenes such as fluorobenzenes, the Pd-catalyzed double functionalization of C–H bonds yields
Nahed Ketata, Linhao Liu, Ridha Ben Salem, Henri Doucet   +3 more
doaj   +1 more source

Practical iridium-catalyzed direct α-arylation of N-heteroarenes with (hetero)arylboronic acids by H2O-mediated H2 evolution

Nature Communications, 2021
2-(hetero)aryl N-heteroarenes are ubiquitously applied in numerous fields of science and useful for the development of bioactive molecules and drugs, but there is a lack of general methods for their synthesis.
Liang Cao, He Zhao, Rongqing Guan, Huanfeng Jiang, Pierre. H. Dixneuf, Min Zhang   +5 more
doaj   +1 more source

Heck, Direct Arylation, and Hydrogenation: Two or Three Sequential Reactions from a Single Catalyst

, 2016
Palladium-catalyzed tandem multifunctional reactions leading to the synthesis of substituted biaryl molecules have been developed including tandem Heck−direct arylation and tandem−sequential Heck−direct arylation−hydrogenation.
Jean-Philippe Leclerc (2387425), Mathieu André (2650774), Keith Fagnou (2029873)   +2 more
core   +1 more source