Results 111 to 120 of about 3,248,511 (314)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
A Review of Safety Economics Studies and Cost of Occupational Accidents in Iran from 2000 to 2021
بهداشت و ایمنی کار, 2022 Introduction: Due to occupational accidents, many costs are annually lost from the countries’ Gross Domestic Product (GDP). Estimating these costs can be essential for optimal investments and establishing appropriate policies in many countries, such as ...
Younes Mehrifar +6 more
doaj
Confronting California's Rent and Poverty Crisis: A Call for State Reinvestment in Affordable Homes [PDF]
, 2016 Too many California families are falling into poverty because of high housing costs. The California Housing Partnership calls on state leaders to take direct, immediate action to reinvest in affordable homes in California.
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Evaluating the direct costs of controlling NOx emissions in Europe [PDF]
This study summarises the available information on the costs of those nitrogen oxides abatement technologies in operation at present or coming into operation in the near future.
Halkos, George
core +1 more source
The costs of poor safety in the workplace [PDF]
, 1997 Over the last two years we have conducted research on the costs of accidents in the workplace, monitoring 14 firms in the Republic of Ireland (RoI) over a 12 week period in 1995, and 11 firms in Northern Ireland (NI) over a 12 week period in 1996. Using
Jacobson, David, Mottiar, Ziene
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Current knowledge of morbidities and direct costs related to diabetic foot disorders: a literature review. [PDF]
Front Endocrinol (Lausanne), 2023 Waibel FWA +4 more
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source