Results 31 to 40 of about 3,481,790 (282)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Conceptualizing and Measuring the Quality of Democracy: The Citizens’ Perspective
Politics and Governance, 2018 In recent years, several measurements of the quality of democracy have been developed (e.g. Democracy Barometer, Varieties of Democracy Project). These objective measurements focus on institutional and procedural characteristics of democracy.
Dieter Fuchs, Edeltraud Roller
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
, 2011 oai:democracyeducationjournal.org:home-1000There is a widespread movement today to prepare all students for college, and it is promoted in the name of democracy.
Noddings, Nel
core +1 more source
Direct and Representative Democracy. The Debate in Revolutionary France (1789-1795)
Scienza & Politica, 2017 This essay explores the debate concerning the idea of democracy in the French Revolution (1789-1795). It shows that this idea is based upon representative democracy as well as direct democracy, maintaining a complex and precarious equilibrium between the
Antonio Senta
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Improving Democracy Education. A Book Review of \u3ci\u3eEducation for Democracy: A Renewed Approach to Civic Inquiries for Social Justice\u3c/i\u3e [PDF]
, 2022 In their book Education for Democracy: A Renewed Approach to Civic Inquiries for Social Justice, authors Steven P. Camicia and Ryan Knowles (2021) offer a timely recipe for addressing the lack of civic competence in America, which is facing a great ...
Sims, Lillian +5 more
core +1 more source
Вісник Харківського національного університету імені В. Н. Каразіна Серія: «Право», 2022 Introduction. The article deals with the study of the essence and features of participatory democracy as one of the political and legal foundations of municipal power.
Oleksiy Ganzhuk
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Determinants of Direct Democracy [PDF]
This paper investigates on the demographic, economic, political and cultural determinants of direct democracy in 87 countries using an index of direct democracy.
Roberto Ricciuti, Nadia Fiorino
core +2 more sources