Results 41 to 50 of about 3,481,790 (282)

Weber’s Concern on Immediate Democracy and the Mediation of Parliament

open access: yesRedescriptions, 2020
Weber’s judgement on the types of immediate democracy is ambivalent; he recognizes the reduction of institutional mediation and power as well as the possibility of a more direct intervention by the people on the one hand, but he also underlines the major
Cristiana Senigaglia
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Explaining institutional change : why elected politicians implement direct democracy [PDF]

open access: yes, 2010
Why did representative politicians introduce direct democratic reforms, thus binding their own hands? This paper presents a formal model in which (1) voters are uncertain about their representative’s preferences; (2) direct and representative ...
Hugh-Jones, David
core  

Equality as the name of democracy - Bogdana Koljević: Democracy of contemporary French poststructuralism, Serbian State Publisher of Textbooks, Belgrade, 2018 [PDF]

open access: yesSociološki Pregled, 2019
This exceptional book for our public opens dilemmas about the potential of democracy as it is, an opinion which is frequently taken for granted or rejected here, in a rather arbitrary manner.
Bratina Boris R.
doaj  

Direct Democracy in Lithuania

open access: yes, 2018
The conducted research positively verified the hypothesis assumed that in Lithuania direct democracy functions in the legal and formal as well as practical dimension. It should be pointed out though that the constitutional and statutory provisions regulate the institutions of direct democracy only on a national level while there are no solutions that ...
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The Legal Limits of Direct Democracy

open access: yes, 2021
With the rise of direct-democratic instruments, the relationship between popular sovereignty and the rule of law is set to become one of the defining political issues of our time. This important and timely book provides an in-depth analysis of the limits

core   +1 more source

Does direct democracy increase civic virtues? A systematic literature review

open access: yesFrontiers in Political Science
Due to widespread citizen disenchantment with representative democracy, the introduction of direct-democratic institutions is often promoted as a promising remedy to overcome the current democratic crisis. Theorists of participatory democracy have argued
Laurent Bernhard
doaj   +1 more source

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