Results 121 to 130 of about 1,605,931 (317)

Directional statistics for WIMP direct detection

, 2004
The direction dependence of the event rate in WIMP direct detection experiments provides a powerful tool for distinguishing WIMP events from potential backgrounds. We use a variety of (non-parametric) statistical tests to examine the number of events required to distinguish a WIMP signal from an isotropic background when the uncertainty in the ...
Morgan, Ben, Green, Anne M., Spooner, Neil J. C.   +2 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

INVESTIGATIONS INTO THE NATURE OF DARK MATTER AND ITS POTENTIAL INTERACTIONS WITH OTHER PARTICLES

Worldwide Journal of Physics
Background: Despite constituting approximately 27% of the total mass-energy content of the universe, the fundamental nature of dark matter remains one of the most pressing mysteries in modern physics.
Altaf Karim, Muhammad Nouman Sarwar Qureshi   +1 more
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Development of a novel method for detection of C. difficile using HS-SPME-GC-MS

, 2014
AIMS:A novel method has been developed that allows successful differentiation between Clostridium difficile culture-positive and culture-negative stool samples based on volatile organic compound (VOC) evolution and detection by headspace solid-phase ...
Dean, John, Stanforth, Stephen, Tait, Emma, Hill, Kerry, Perry, John   +4 more
core   +1 more source

Research Progress on Carrier-Free Phase-Retrieval Receivers

Photonics
In order to deal with the chromatic dispersion-induced power fading issue for short-reach direct-detection optical fiber communication applications, such as the ever-increasing data-center interconnections (DCIs), optical filed recovery is intensively ...
Yunhe Ma, Meng Xiang, Xiaoxue Gan, Can Wei, Wenzhuo Cheng, Gai Zhou, Jilong Li, Jianping Li, Songnian Fu, Yuwen Qin   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

High spectral efficiency SSB-PAM-DD scheme with high linewidth tolerance

Tongxin xuebao, 2022
For low-cost and high chromatic dispersion (CD) robustness single sideband (SSB) with direct detection (DD), three schemes of SSB with pulse amplitude modulation (PAM) were investigated.Among that, the highest spectral efficiency was achieved by the ...
Dongxu LU, Xian ZHOU, Fei LIU, Jiahao HUO, Jinhui YUAN, Keping LONG   +5 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source