Results 131 to 140 of about 3,454,909 (295)

High spectral efficiency SSB-PAM-DD scheme with high linewidth tolerance

Tongxin xuebao, 2022
For low-cost and high chromatic dispersion (CD) robustness single sideband (SSB) with direct detection (DD), three schemes of SSB with pulse amplitude modulation (PAM) were investigated.Among that, the highest spectral efficiency was achieved by the ...
Dongxu LU, Xian ZHOU, Fei LIU, Jiahao HUO, Jinhui YUAN, Keping LONG   +5 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Advanced optical receiver architectures for ultra-high capacity but low-cost short-reach optical interconnects

Dianxin kexue, 2022
The deployment of emerging network infrastructure such as hyper-scale datacenters urgently requires ultra-high capacity but low-cost short-reach optical interconnects.Conventional intensity modulation and direct detection possesses a simple receiver ...
Honglin JI, Xueyang LI, Zhixue HE, Weisheng HU, Shieh William   +4 more
doaj  

Calculation of Receiver Sensitivities in (Orthogonal) Subcarrier Multiplexing Microwave-Optical Links

Applied Sciences, 2017
Microwave-based all-analogue (orthogonal) subcarrier multiplexing (SCM) permits a direct processing of baseband data at Gbit/s while achieving low power consumption, low latency, low cost, and tolerance to dispersion.
Fernando A. Gutiérrez, Eamonn P. Martin, Philip Perry, Andrew D. Ellis, Liam P. Barry   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Comprehensive Comparison of Simplified Volterra Equalization and Kramers–Kronig Schemes in 200 Gb/s/λ PON Downlink Transmission

Photonics
The emerging high-bandwidth services of 6G, such as high-definition video transmission and real-time interaction, have promoted the progress of the fiber optic access network industry, driving its development towards the next-generation PON with higher ...
Hao Yang, Huanran Su, Tao Yang, Guan Wang, Yun Xie, Liuke Yi, Xingang Huang, Zhuang Ma, Yiming Zhong, Xiatao Huang, Bo Liu   +10 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source