Results 161 to 170 of about 1,605,931 (317)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Single photodiode-based direct detection for Twin-SSB-QPSK signal in optical fiber communication systems

Tongxin xuebao
To address the high-cost issue of twin single sideband quadrature phase shift keying (Twin-SSB-QPSK) signals in optical transmission, a optical fiber communication system was proposed, in which a single photodetector (PD) was employed at the receiver to ...
ZHANG Hongbo, LIU Jiao, LING Weiwei, ZHANG Min, WAN Feng, CAI Ju   +5 more
doaj  

Optical Triple-Band Multiplexing Enabling Beyond-600 Gb/s Single-Photodiode Reception for Intra-AIDC Interconnects

Photonics
Generative artificial intelligence (AI) models including GPT, Gemini, and DeepSeek are reshaping embodied agents, temporal prediction, and autonomous driving, demanding a ten-fold annual growth in training FLOPS that Moore’s law can no longer sustain ...
Ziheng Zhang, Yixiao Zhu, Xiang Cai, Xiansong Fang, Chenbo Zhang, Yimin Hu, Lingjun Zhou, Chongyu Wang, Fan Zhang, Weisheng Hu   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Direct determination of sialic acids in serum by capillary electrophoresis with UV detection

, 2000
A novel method for the determination of N-acetylneuraminic acid (NANA) and N-glycolylneuraminic acid (NGNA) has been developed using high-performance capillary electrophoresis with UV detection at 195 nm, without pre or post-column derivatisation.
Dong, XL, Xu, Y, Lin, BC
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Performance of Hybrid Direct-Sequence Time-Hopping Ultrawide Bandwidth Systems over Nakagami-m Fading Channels

, 2007
This paper investigates and compares the performance of various ultrawide bandwidth (UWB) systems when communicating over Nakagami-m fading channels. Specifically, the direct-sequence (DS), time-hopping (TH) and hybrid direct-sequence time-hopping (DS-TH)
Yang, Lie-Liang, Ahmed, Qasim Zeeshan
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Subspace discovery for video anomaly detection

, 2010
PhDIn automated video surveillance anomaly detection is a challenging task. We address this task as a novelty detection problem where pattern description is limited and labelling information is available only for a small sample of normal instances.
Tziakos, Ioannis
core