Results 121 to 130 of about 9,120,926 (345)

Experimental investigation of direct myocardial protective effect of atrial natriuretic peptide in cardiac surgery [PDF]

open access: bronze, 2009
Shinji Wakui   +7 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Features of Limiting State Diagrams for Active Systems under Mechano-Sliding Fatigue

open access: yesМеханика машин, механизмов и материалов
Experimental diagrams of limiting states of active systems under conditions of mechano-sliding fatigue are presented, as well as their analytical description.
Alexander V. Bogdanovich
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The contribution of the diffuse light component to the topographic effect on remotely sensed data [PDF]

open access: yes
The topographic effect is measured by the difference between the global radiance from inclined surfaces as a function of their orientation relative to the sensor position and light source.
Holben, B., Justice, C.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Corrosion-Mechanical Fatigue: the Problems of Forecasting. Part 3. Mechanisms of Corrosion-Mechanical Fatigue

open access: yesМеханика машин, механизмов и материалов
Corrosion is one of the main electrochemical processes that damage metal materials. The combination of cyclic stresses and a corrosive environment causes wear-fatigue damage, called corrosion-mechanical fatigue.
Leonid A. Sosnovskiy   +2 more
doaj   +1 more source

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