Results 141 to 150 of about 3,157,646 (265)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Corrigendum: Lipid have a direct effect on multiple myeloma: a Mendelian randomization study. [PDF]

Front Oncol
Zhong Y, Li Y, Sun W, Xiao M.
europepmc   +1 more source

Spores of Trichoderma Strains over P. vulgaris Beans: Direct Effect on Insect Attacks and Indirect Effect on Agronomic Parameters. [PDF]

Insects, 2022
Rodríguez-González Á, Carro-Huerga G, Guerra M, Mayo-Prieto S, Porteous-Álvarez AJ, Lorenzana A, Campelo MP, Fernández-Marcos A, Casquero PA, Gutiérrez S.   +9 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Does the direct effect of friction increase continuously with absolute temperature? [PDF]

Proc Natl Acad Sci U S A
Barbot S.
europepmc   +1 more source

Estimating the Direct Effect between Dietary Macronutrients and Cardiometabolic Disease, Accounting for Mediation by Adiposity and Physical Activity. [PDF]

Nutrients, 2022
Pomares-Millan H, Atabaki-Pasdar N, Coral D, Johansson I, Giordano GN, Franks PW.   +5 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3-Way Crossover Trial. [PDF]

Clin Pharmacol Ther
Gorbenko AA, de Cuba CMKE, de Goede AA, Post TE, Bohoslavsky R, Strugala PK, Heuberger JAAC, Groeneveld GJ.   +7 more
europepmc   +1 more source

May position of hemodialysis catheter tip have a direct effect on its patency? Positive results of a preliminary study on its rotation. [PDF]

Eur J Transl Myol, 2022
Hassani M, Mohebbi M, Tavallaei M, Nodoushan SMRH, Mirzadeh M, Hashemi R.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source