Results 121 to 130 of about 3,157,646 (265)

17β-estradiol does not have a direct effect on the function of striatal cholinergic interneurons in adult mice in vitro. [PDF]

Front Endocrinol (Lausanne), 2022
Kövesdi E, Udvarácz I, Kecskés A, Szőcs S, Farkas S, Faludi P, Jánosi TZ, Ábrahám IM, Kovács G.   +8 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The effectiveness of red-light therapy on myopia control depends on its direct effect: a mediation analysis. [PDF]

J Transl Med
Chen Q, Wei H, Soh ZD, Zhu Q, Shao X, Xue C, Li H, Tao Y, Hu M, Cheng CY, Zhong H.   +10 more
europepmc   +1 more source

Genome-Wide Gene Expression Profiling Reveals the Direct Effect of Dienogest on Ovarian Endometriotic Stromal Cells. [PDF]

Reprod Sci, 2023
Honda H, Nishimichi N, Kaneko M, Yamashita M, Akimoto Y, Tanimoto H, Teramoto M, Teramoto H, Yokosaki Y.   +8 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A direct effect of sulfatide against development of fibrosis. [PDF]

Metabol Open
Thea R, Buschard K.
europepmc   +1 more source

Bacillus vallismortis TU-Orga21 blocks rice blast through both direct effect and stimulation of plant defense. [PDF]

Front Plant Sci, 2023
Thepbandit W, Srisuwan A, Siriwong S, Nawong S, Athinuwat D.   +4 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Study of the Direct Effect of Pegylated Graphene Oxide Nanoparticles and Fullerenol C₆₀(OH)₂₄ on the Differentiation of Regulatory T Cells In Vitro. [PDF]

Nanomaterials (Basel)
Zamorina S, Usanina D, Devyatova K, Bochkova M, Nikitina M, Rayev M, Timganova V.   +6 more
europepmc   +1 more source

The direct effect of drinking to cope on alcohol problems is not mediated by alcohol consumption: Invariance across gender and countries. [PDF]

Addict Behav Rep, 2022
Shuai R, Bravo AJ, Anker JJ, Kushner MG, Hogarth L.   +4 more
europepmc   +1 more source