Results 161 to 170 of about 9,147,726 (300)

Bacillus vallismortis TU-Orga21 blocks rice blast through both direct effect and stimulation of plant defense. [PDF]

Front Plant Sci, 2023
Thepbandit W, Srisuwan A, Siriwong S, Nawong S, Athinuwat D.   +4 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A direct effect of sulfatide against development of fibrosis. [PDF]

Metabol Open
Thea R, Buschard K.
europepmc   +1 more source

The direct effect of drinking to cope on alcohol problems is not mediated by alcohol consumption: Invariance across gender and countries. [PDF]

Addict Behav Rep, 2022
Shuai R, Bravo AJ, Anker JJ, Kushner MG, Hogarth L.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Novel direct effect of CCR2 receptor on follicle activation process. [PDF]

Front Endocrinol (Lausanne)
Gamaleri Y, Ferman DS, Ting A, Dascal ER, Lomniczi A, Jaworski JP, Peluffo MC.   +6 more
europepmc   +1 more source

Direct effect of lipopolysaccharide and histamine on permeability of the rumen epithelium of steers ex vivo. [PDF]

J Anim Sci, 2022
Gao S, Zhula A, Liu W, Lu Z, Shen Z, Penner GB, Ma L, Bu D.   +7 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of the direct effect of remote ischemic preconditioning on the rabbit's kidney by R₂' mapping technique: an experimental study. [PDF]

BMC Med Imaging
Bi Z, Xing Z, Huang L, Yu X, Ding J, Chen J, Xing W, Pan L.   +7 more
europepmc   +1 more source

Profound Sensitivity of the Liver to the Direct Effect of Insulin Allows Peripheral Insulin Delivery to Normalize Hepatic but Not Muscle Glucose Uptake in the Healthy Dog. [PDF]

Diabetes, 2023
Kraft G, Coate KC, Smith M, Farmer B, Scott M, Hastings J, Cherrington AD, Edgerton DS.   +7 more
europepmc   +1 more source