Results 171 to 180 of about 9,105,244 (296)

Corrigendum: Lipid have a direct effect on multiple myeloma: a Mendelian randomization study. [PDF]

Front Oncol
Zhong Y, Li Y, Sun W, Xiao M.
europepmc   +1 more source

Estimating the Direct Effect between Dietary Macronutrients and Cardiometabolic Disease, Accounting for Mediation by Adiposity and Physical Activity. [PDF]

Nutrients, 2022
Pomares-Millan H, Atabaki-Pasdar N, Coral D, Johansson I, Giordano GN, Franks PW.   +5 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3-Way Crossover Trial. [PDF]

Clin Pharmacol Ther
Gorbenko AA, de Cuba CMKE, de Goede AA, Post TE, Bohoslavsky R, Strugala PK, Heuberger JAAC, Groeneveld GJ.   +7 more
europepmc   +1 more source

May position of hemodialysis catheter tip have a direct effect on its patency? Positive results of a preliminary study on its rotation. [PDF]

Eur J Transl Myol, 2022
Hassani M, Mohebbi M, Tavallaei M, Nodoushan SMRH, Mirzadeh M, Hashemi R.   +5 more
europepmc   +1 more source

Bounds for Pure Direct Effect [PDF]

Epidemiology, 2014
Eric J, Tchetgen Tchetgen, Kelesitse, Phiri   +1 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Does the direct effect of friction increase continuously with absolute temperature? [PDF]

Proc Natl Acad Sci U S A
Barbot S.
europepmc   +1 more source

Direct effect of RFRP-3 microinjection into the lateral ventricle on the hypothalamic kisspeptin neurons in ovariectomized estrogen-primed rats. [PDF]

Exp Ther Med, 2022
Cheng L, Yang S, Si L, Wei M, Guo S, Chen Z, Wang S, Qiao Y.   +7 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source