Results 41 to 50 of about 3,157,646 (265)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Correlation and path coefficient studies in barley (Hordeum vulgare L.) under dual purpose condition [PDF]

open access: yesElectronic Journal of Plant Breeding, 2013
Twenty two barley genotypes were evaluated for green fodder yield, grain yield and related morphological characters. Plant height, spike length, number of spikelets per spike, number of grains per spike, number of tillers per meter row length and test ...
Mahender Kumar and S. S. Shekhawat
doaj  

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Path coefficient analysis studies in rice (Oryza sativa L.) for quantitative and qualitative traits

open access: yesElectronic Journal of Plant Breeding, 2019
Path coefficient studies were carried out for yield and quality traits in 74 rice genotypes involving hybrids and their parental lines. Grains per panicle, productive tillers per plant and amylose content were significant and positive direct effects on ...
R. Arulmozhi and A. Muthuswamy
doaj   +1 more source

A direct adverse effect of smoking

open access: yesRespiratory Medicine Case Reports, 2021
Smoking has been accounted for numerous adverse effects. We report a direct effect of smoking in a 73-year-old patient, a heavy smoker who presented to the emergency department with a 48-h history of productive cough and fever. Chest x-ray and chest CT revealed right lung infiltrates; however, they were not suggestive of the diagnosis, which was ...
Christos Kyriakopoulos   +3 more
openaire   +3 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Why Do So Few Preliminary Questions Come From Czechia?

open access: yesWroclaw Review of Law, Administration and Economics
Although a substantial part of the body of laws of an EU Member State is founded upon European Union law and norms, the number of preliminary questions emanating from courts in the Czech Republic appears to be disproportionately low compared to other ...
Kunertová Tereza
doaj   +1 more source

Fallibility in estimating direct effects [PDF]

open access: yesInternational Journal of Epidemiology, 2002
We use causal graphs and a partly hypothetical example from the Physicians' Health Study to explain why a common standard method for quantifying direct effects (i.e. stratifying on the intermediate variable) may be flawed. Estimating direct effects without bias requires that two assumptions hold, namely the absence of unmeasured confounding for (1 ...
Stephen R, Cole, Miguel A, Hernán
openaire   +2 more sources

Home - About - Disclaimer - Privacy