Results 61 to 70 of about 8,286 (265)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Exchange Rates and Outward Foreign Direct Investment: US FDI in Emerging Economies [PDF]
The paper investigates the impact of exchange rates on US foreign direct investment (FDI) flows to a sample of 16 emerging market countries using annual panel data for the period 1990-2002.
Udomkerdmongkol, Manop +2 more
core
DETERMINANTS OF COCOA EXPORT EARNINGS IN NIGERIA (1980-2019) [PDF]
This study investigated the determinants of cocoa export earnings in Nigeria between 1980 and 2019. Secondary data spanning between 1980 and 2019 were collected from reputable sources such as Food and Agriculture Organisation Statistical Database ...
Ahmed BUSARI +3 more
doaj
Direct Investment, Hysteresis, and Real Exchange Rate Volatility
Abstract Recent papers by Dixit and others have put forth the argument that real exchange shocks generate a condition of hysteresis in the export entry and exit prices, and that this wedge in prices explains the persistence in the U.S. current account deficit. This article shows that the critical hysteresis bounds for exports are altered dramatically
Nalin Kulatilaka, Bruce Kogut
openaire +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
FOREIGN DIRECT INVESTMENT AND EXCHANGE RATES: A CASE STUDY OF U.S. FDI IN EMERGING MARKET COUNTRIES [PDF]
This paper investigates the impact of exchange rates on US Foreign Direct Investment (FDI)inflows to a sample of 16 emerging market countries using panel data for the period 1990-2002.
Holger Görg +2 more
core
The purpose of this study is to determine the influence of macroeconomic factors (inflation and exchange rates) and monetary policy (interest rates and money supply) on the growth of Islamic fintech in Indonesia.
Muhammad Zaki As Shafi MT
doaj +1 more source

