Results 71 to 80 of about 1,585,379 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

DETERMINANTS OF COCOA EXPORT EARNINGS IN NIGERIA (1980-2019) [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2022
This study investigated the determinants of cocoa export earnings in Nigeria between 1980 and 2019. Secondary data spanning between 1980 and 2019 were collected from reputable sources such as Food and Agriculture Organisation Statistical Database ...
Ahmed BUSARI, Olaide AKINTUNDE, Timothy AGBOOLA, Lateef JIMOH   +3 more
doaj  

Impact ionization in GaAs: a screened exchange density functional approach

, 2001
Results are presented of a fully ab-initio calculation of impact ionization rates in GaAs within the density functional theory framework, using a screened-exchange formalism and the highly precise all-electron full-potential linearized augmented plane ...
A. Continenza, A. J. Freeman, A. Seidl, C.B. Geller, C.B. Geller, D. Harrison, D. Harrison, D.M. Bylander, E. Wimmer, G. Cappellini, G. E. Bulman, H.J. Monkhorst, H.K. Jung, J. Bude, M. Stobbe, M.L. Cohen, N. Sano, P. Hohenberg, R. Asahi, R. Asahi, R. Redmer, S. Massidda, S. Picozzi, T.P. Humphreys, W. Kohn, Y. Wang   +25 more
core   +1 more source

Exchange Rate Variability and Foreign Direct Investment – Consequences of EMU Enlargement [PDF]

SSRN Electronic Journal, 2003
The aim of the paper is to analyze theoretically and empirically the likely impact of the reduction in exchange rate uncertainty, due to the EMU accession, on the intensity of FDI inflow into candidate countries. Theoretical models give an ambiguous picture of how exchange rate uncertainty and volatility affect direction and magnitude of FDI inflows ...
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

DETERMINANTS OF SHARIA FINTECH GROWTH IN INDONESIA: AN INTEGRATIVE ANALYSIS OF MACROECONOMIC INDICATORS AND MONETARY POLICY

I-Finance
The purpose of this study is to determine the influence of macroeconomic factors (inflation and exchange rates) and monetary policy (interest rates and money supply) on the growth of Islamic fintech in Indonesia.
Muhammad Zaki As Shafi MT
doaj   +1 more source

Entry, Multinational Firms, and Exchange Rate Volatility [PDF]

Recent discussions of exchange rate determination have emphasized the possible role of foreign direct investment in influencing exchange rate behavior. Yet, there are few existing models of multinational enterprises (MNEs) and endogenous exchange rates.
Katheryn N. Russ, Thomas A. Lubik
core  

Exchange Rate Movements, Foreign Direct Investment, and Domestic R&D

Research in World Economy, 2015
This paper develops a game-theoretical model to investigate heterogeneous firms’ entry mode choice of international expansion. The distinct feature of this paper is that exchange rate, R&D competition, and intra-industry firm heterogeneity are incorporated into the theoretical framework. The possible impact of a firm’s outward foreign direct investment
Kun-Ming Chen, Chia-Ching Lin, Shu-Fei Yang   +2 more
openaire   +4 more sources