Results 71 to 80 of about 8,286 (265)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Exchange Rates and U.S. Direct Investment into Latin America [PDF]

This paper analyzes the impact of exchange rate levels and exchange rate uncertainty on U.S. foreign direct investment into Latin America. By decomposing exchange rate uncertainty into temporary (short-run) and permanent (long-run) components, we further
Isabel Ruiz, Susan Pozo
core  

A moderation analysis of the effect of international tourism on economic growth in Sub-Saharan Africa

Cogent Economics & Finance
While the direct effect of international tourism on economic growth has been widely studied, limited attention has been given to the macroeconomic conditions that moderate this effect.
Rose Kibuuka Nakimu, John Bbale Mayanja, Aisha Nanyiti   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Exchange rates and FDI: Goods versus capital market frictions [PDF]

Economic theory provides two main explanations why changes in exchange rates can affect foreign direct investment (FDI). According to a first explanation, FDI reacts to exchange rate changes if there are information frictions on capital markets and if ...
Buch, Claudia M., Kleinert, Jörn
core  

Determinants of agricultural exports in Somalia: the impacts of exchange rates, foreign direct investment, and institutional quality

Cogent Economics & Finance
Globally, the exportation of agricultural products plays a critical role in driving economic growth and stability, often acting as a substantial contributor to gross domestic product (GDP), employment, and foreign exchange earnings in agrarian economies.
Abdikafi Hassan Abdi, Amir Mohamud Mohamed   +1 more
doaj   +1 more source

Views on marketization reform direction of China's interest rate and exchange rate

Advances in Computer Science Research, 2014
Economic reform is the core of deepening the reform of our country nowadays, and this paper will focus on the marketization reform direction of China's interest rate and exchange rate. This paper starts from domestic and international economic environment, facing the marketization reform of China's interest rate and exchange rate.
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Exchange rate policy in Republic of Serbia in conditions of the global economic crisis and Covid-19 pandemic: Similarities and differences [PDF]

Trendovi u Poslovanju
The foreign exchange market represents the direct connection between a national economy and the global environment. The smooth functioning of the foreign exchange market contributes to national financial markets increasingly establishing relationships ...
Dimić Maja, Stanković Ljiljana, Todorović Milica   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source