Results 81 to 90 of about 2,076,692 (292)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

VecGAN: Image-to-Image Translation with Interpretable Latent Directions

, 2022
We propose VecGAN, an image-to-image translation framework for facial attribute editing with interpretable latent directions. Facial attribute editing task faces the challenges of precise attribute editing with controllable strength and preservation of the other attributes of an image.
Dalva, Yusuf, Dundar, Aysegul, Altındiş, Said Fahri   +2 more
openaire   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Sensitivity of synthetic aperture laser optical feedback imaging

, 2012
In this paper we compare the sensitivity of two imaging configurations both based on Laser Optical Feedback Imaging (LOFI). The first one is direct imaging, which uses conventional optical focalisation on target and the second one is made by Synthetic ...
Aleksoff, Bramati, Day, Dubois, Dubois, Eric Lacot, Hugon, Hugon, Hugon, Hugues Guillet de Chatellus, Jacquin, Jacquin, Jacquin, Kolobov, Lacot, Lacot, Lacot, Liu, Markus, Minsky, Muzet, Olivier Hugon, Olivier Jacquin, Otsuka, Otsuka, Pantazis, Pernot, Popoff, Sudo, Vellekoop, Vertu, Wilfried Glastre, Witomski, Witomski   +33 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Direct detection of label-free blood fingermarks by SECM imaging

Electrochemistry Communications, 2019
A label-free strategy for imaging blood fingermarks (BFMs) on a hydrophobic poly(vinylidene difluoride) (PVDF) membrane has been developed using scanning electrochemical microscopy (SECM) in the surface interrogation (SI) mode.
Lu Tian, Xiaohui Wang, Liang Zhao, Mi Shi, Hongjuan Wang, Xueji Zhang, Meiqin Zhang   +6 more
doaj   +1 more source

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

FEBS Letters, EarlyView.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Orbital and Atmospheric Modeling of H ii 1348B: An Eccentric Young Substellar Companion in the Pleiades

The Astronomical Journal
Brown dwarfs with known physical properties (e.g., age and mass) are essential for constraining models of the formation and evolution of substellar objects.
Gabriel Weible, Kevin Wagner, Jordan Stone, Steve Ertel, Dániel Apai, Kaitlin Kratter, Jarron Leisenring   +6 more
doaj   +1 more source

Advanced Aortic Imaging: Future Directions

Methodist DeBakey Cardiovascular Journal, 2011
There have been dramatic advances in aortic imaging over the last decade. Some of these capabilities have been driven by the development of aortic endografts, the need for accurate measurement of aortic dimensions, and capabilities for simulating endograft placement.
Alan B, Lumsden, Christof, Karmonik, Christopher J, Smolock, Jean, Bismuth   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source