Results 71 to 80 of about 4,947,056 (252)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Direct detection of label-free blood fingermarks by SECM imaging
Electrochemistry Communications, 2019 A label-free strategy for imaging blood fingermarks (BFMs) on a hydrophobic poly(vinylidene difluoride) (PVDF) membrane has been developed using scanning electrochemical microscopy (SECM) in the surface interrogation (SI) mode.
Lu Tian +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Astronomical JournalBrown dwarfs with known physical properties (e.g., age and mass) are essential for constraining models of the formation and evolution of substellar objects.
Gabriel Weible +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
AFM imaging of functionalized carbon nanotubes on biological membranes [PDF]
, 2009 Multifunctional carbon nanotubes are promising for biomedical applications as their nano-size, together with their physical stability, gives access into the cell and various cellular compartments including the nucleus.
Coley, Helen M. +38 more
core +1 more source
The Astronomical JournalWe present and analyze follow-up, higher resolution ( R ∼ 70) H and K band integral field spectroscopy of the superjovian exoplanet HIP 99770 b with SCExAO/CHARIS.
Danielle Bovie +14 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Impacts of Correlated Noise on Retrievals of Exo-Earth Atmospheres
The Astronomical JournalThe Habitable Worlds Observatory (HWO) aims to accomplish high-contrast imaging and spectroscopy of true Earth analogs for the first time. However, high-contrast spectroscopy with HWO may be limited by residual speckles, which persist after deformable ...
Nicole Wolff +8 more
doaj +1 more source
Direct imaging of LaAlO3/SrTiO3 nanostructures using piezoresponse force microscopy
APL Materials, 2013 The interface between LaAlO3 and TiO2-terminated SrTiO3 can be switched between metastable conductive and insulating states using a conductive atomic force microscope probe.
Mengchen Huang +5 more
doaj +1 more source