Results 81 to 90 of about 1,136,956 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
VecGAN: Image-to-Image Translation with Interpretable Latent Directions
We propose VecGAN, an image-to-image translation framework for facial attribute editing with interpretable latent directions. Facial attribute editing task faces the challenges of precise attribute editing with controllable strength and preservation of the other attributes of an image.
Dalva, Yusuf +2 more
openaire +4 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Objective: A breast imaging nurse navigator (NN) was established with the goals to enhance the patient experience after biopsy, improve care timeliness, accuracy, and coordination, facilitate direct communication to patients, and increase care retention ...
Mehta, Tejas S +5 more
core +1 more source
We report the results from a pilot study to search for black holes and other dark companions in binary systems using direct imaging with SHARK-VIS and the iLocater pathfinder “Lili” on the Large Binocular Telescope.
D. M. Rowan +17 more
doaj +1 more source
Fast Directional Image Completion [PDF]
We developed a fast image completion system using the multiresolution approach to accelerate the convergence of the system. The down-sampling approach is for the texture-eigenspace training process based on the multi-level background region information.
Chih-Wei Fang, Jenn-Jier James Lien
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
We present new VLTI/GRAVITY astrometry and updated orbit fits for the directly imaged companions YSES 1 b and HR 2562 B, substellar objects straddling the planet–brown-dwarf boundary.
Jonathan Roberts +22 more
doaj +1 more source
Direct 3D Mass Spectrometry Imaging Analysis of Environmental Microorganisms
Assessing the spatial distribution of microorganisms’ metabolites in growth medium remains a challenge. Here, we present the first use of the newly developed LARAPPI/CI-MSI 3D (laser ablation remote atmospheric pressure photoionization/chemical ...
Justyna Szulc +5 more
doaj +1 more source
Direct imaging of LaAlO3/SrTiO3 nanostructures using piezoresponse force microscopy
The interface between LaAlO3 and TiO2-terminated SrTiO3 can be switched between metastable conductive and insulating states using a conductive atomic force microscope probe.
Mengchen Huang +5 more
doaj +1 more source

