Results 81 to 90 of about 2,104,910 (277)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

VecGAN: Image-to-Image Translation with Interpretable Latent Directions

open access: yes, 2022
We propose VecGAN, an image-to-image translation framework for facial attribute editing with interpretable latent directions. Facial attribute editing task faces the challenges of precise attribute editing with controllable strength and preservation of the other attributes of an image.
Dalva, Yusuf   +2 more
openaire   +4 more sources

Constraints for the Progenitor Masses of 17 Historic Core-Collapse Supernovae

open access: yes, 2014
Using resolved stellar photometry measured from archival HST imaging, we generate color-magnitude diagrams of the stars within 50 pc of the locations of historic core-collapse supernovae that took place in galaxies within 8 Mpc.
Dalcanton, Julianne J.   +6 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Direct detection of label-free blood fingermarks by SECM imaging

open access: yesElectrochemistry Communications, 2019
A label-free strategy for imaging blood fingermarks (BFMs) on a hydrophobic poly(vinylidene difluoride) (PVDF) membrane has been developed using scanning electrochemical microscopy (SECM) in the surface interrogation (SI) mode.
Lu Tian   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Self-coherent camera as a focal plane wavefront sensor: simulations

open access: yes, 2009
Direct detection of exoplanets requires high dynamic range imaging. Coronagraphs could be the solution, but their performance in space is limited by wavefront errors (manufacturing errors on optics, temperature variations, etc.), which create quasi ...
Baudoz, Pierre   +4 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Orbital and Atmospheric Modeling of H ii 1348B: An Eccentric Young Substellar Companion in the Pleiades

open access: yesThe Astronomical Journal
Brown dwarfs with known physical properties (e.g., age and mass) are essential for constraining models of the formation and evolution of substellar objects.
Gabriel Weible   +6 more
doaj   +1 more source

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