Results 61 to 70 of about 4,898,176 (272)

Fabrication of multi-scale periodic surface structures on Ti-6Al-4V by direct laser writing and direct laser interference patterning for modified wettability applications

, 2022
S.134-142In this work, hierarchical surface patterns fabricated on Ti-6Al-4V alloy combining two laser micro-machining techniques are presented. The used technologies are based on nanosecond Direct Laser Writing and picosecond Direct Laser Interference ...
Jagdheesh, R., Lasagni, Andrés-Fabián, Cardoso, José Tiago, Aguilar Morales, Alfredo Ismael, Alamri, Sabri, Ocaña, José L., Huerta-Murillo, D.   +6 more
core   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

New Approach for Monitoring a Direct Laser Interference Patterning Process Using a Combination of an Infrared Camera and a Diffraction Measurement System

, 2021
Recently, process monitoring emerges as a breakthrough technology in industrial laser machines applications to enhance process stability and economic efficiency while ensuring high-quality pro-cessing parts and significantly reducing scrap rate ...
Lasagni, Andrés Fabián, Lasagni, Andrés-Fabián, Teutoburg-Weiss, Sascha, Vergara, Germán, Schröder, Nikolai   +4 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Universal Micromachining Platform and Basic Technologies for the Manufacture and Marking of Microphysiological Systems

Micromachines, 2017
Micro Physiological Systems (MPS), also known as Multi-Organ-Chip, Organ-on-a-Chip, or Body-on-a-Chip, are advanced microfluidic systems that allow the cultivation of different types of cells and tissue in just one common circuit.
Katja Günther, Frank Sonntag, Elmar Moritzer, Andrè Hirsch, Udo Klotzbach, Andrés Fabián Lasagni   +5 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

On the Corrosion Properties of Aluminum 2024 Laser‐Textured Surfaces with Superhydrophilic and Superhydrophobic Wettability States

Advanced Materials Interfaces, 2023
In this work, the mechanism of the corrosion behavior of laser‐treated aluminum is studied. Two different laser techniques are used to fabricate the samples, direct laser interference patterning (DLIP) and direct laser writing (DLW), using nanosecond ...
Lis Geraldine Zschach, Robert Baumann, Flavio Soldera, Claudia Marcela Méndez, Sabine Apelt, Ute Bergmann, Andrés Fabián Lasagni   +6 more
doaj   +1 more source

Direct laser interference patterning

, 2022
15 S.Surface pattering engineering techniques are essential to fabricate advanced topographies that can be use to modulate macroscopic properties on different materials.
Lasagni, A.
core   +1 more source