Results 151 to 160 of about 16,317,522 (260)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Direct method for Ra-226 analysis in water samples using ICP-QQQ-MS. [PDF]
Sci RepCoha I, Štrok M, Kavasi N.
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A direct method for imaging gradient levels of retinal hypoxia in a model of retinopathy of prematurity (ROP). [PDF]
BMC OphthalmolUddin MDI, Jamal S, Penn JS.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
DAN budget proposal : master budget, 10/31/99 [recto]
, 1999 Alternate title: D.A.N. budget proposal Alternate title: DAN budget ver 2.xls One of four documents stapled together: (1) "DAN budget proposal," (2) "Budget process proposal ; structure of action/organizing," (3) "Organizing task areas," (4) "Proposed ...
Direct Action Network (DAN)
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Evaluation of a direct method for detecting extended-spectrum β-lactamase using the Cica-beta test on positive blood culture bottles. [PDF]
Microbiol SpectrOkinaka T +9 more
europepmc +1 more source
DAN budget proposal : master budget, 10/31/99 [verso]
, 1999 Alternate title: D.A.N. budget proposal Alternate title: DAN budget ver 2.xls One of four documents stapled together: (1) "DAN budget proposal," (2) "Budget process proposal ; structure of action/organizing," (3) "Organizing task areas," (4) "Proposed ...
Direct Action Network (DAN)
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source