Results 111 to 120 of about 1,512,078 (302)
Direct observation of exciton–exciton interactions
Some photo-physical processes in multichromophore systems might get triggered only if two excitations are present. Here, the authors introduce exciton–exciton-interaction 2D spectroscopy, which is a non-linear optical method that can selectively track ...
Jakub Dostál +5 more
doaj +1 more source
Systematic Direct Observation of Clinical Skills in the Clinical Year
Introduction Direct observation of clinical skills is vital to medical student development. However, direct observation of medical students by faculty is often sporadic, undocumented, and unstandardized.
Jocelyn Schiller +9 more
doaj +1 more source
Direct Observation of Benzoylketenes. [PDF]
Yu. S. Andreichikov +6 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Direct Observation Reassessed [PDF]
Kathryn M, Andolsek, Deborah, Simpson
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Potential of Computer-Assisted Direct Observation Apps [PDF]
Direct behavior observation, i.e., without first creating a video recording, is a challenging, one-shot task. The behavior has to be coded accurately during the situation itself.
Wessel, Daniel
core +1 more source
On the Contribution of Direct Child Observation to Psycho-Analysis [PDF]
In this essay, Winnicott develops further the theme of his paper ‘The Observation of Infants in a Set Situation’ (1941) and re-emphasises the importance of direct observation to psychoanalysis.
Donald W. Winnicott
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

