Results 11 to 20 of about 72,950 (205)

Direct oral anticoagulants uptake and an oral anticoagulation paradox [PDF]

British Journal of Clinical Pharmacology, 2020
Oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation is underutilised. One of the impediments to warfarin therapy is the frequent monitoring required, usually at a specialised warfarin clinic. The advent of direct oral anticoagulants (DOACs) facilitates OAC therapy without an onerous monitoring regimen. This benefit may
Cormac Kennedy, Caitriona Ni Choitir, Sarah Clarke, Kathleen Bennett, Michael Barry   +4 more
openaire   +2 more sources

Thrombocytopenia Induced by Direct Oral Anticoagulants: a Clinical Case and Literature Review

Рациональная фармакотерапия в кардиологии, 2022
The last decade has dramatically changed the strategy of anticoagulant therapy in patients with atrial fibrillation. Direct oral anticoagulants have replaced vitamin K antagonists: either direct thrombin blockers (dabigatran) or factor IIa blockers ...
B. A. Tatarsky, N. V. Kazennova
doaj   +1 more source

Direct oral anticoagulant reversal: An update

Nursing, 2020
Abstract: The rise in direct oral anticoagulant (DOAC) use means nurses must understand the reversal of these agents in case of bleeding. Depending on bleed severity, as well as other criteria, pharmacologic reversal can be considered in place of supportive care alone. Knowledge of literature surrounding DOAC reversal is crucial.
Andrea, Hafer, Lindsay, McCann
openaire   +3 more sources

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand, Förch, Christian, Lindhoff-Last, Edelgard, Mirceska, Ana, Pfeilschifter, Josef Martin (Prof. Dr.), Pfeilschifter, Waltraud, Steinmetz, Helmuth   +6 more
core   +6 more sources

Patient satisfaction after conversion from warfarin to direct oral anticoagulants for patients on extended duration of anticoagulation for venous thromboembolism - The SWAN Study.

PLoS ONE, 2020
BACKGROUND:Warfarin is an anticoagulant medication proven effective in the initial treatment and secondary prevention of venous thromboembolism. Anti-Xa direct oral anticoagulants are alternatives to warfarin; however there is limited data assessing ...
Thomas Hendriks, Scott McGregor, Shilpa Rakesh, Julie Robinson, Kwok M Ho, Ross Baker   +5 more
doaj   +1 more source

Choice of Oral Anticoagulant: Outcomes in Atrial Fibrillation Patients Post-Stroke Despite Direct Oral Anticoagulant Use

CJC Open, 2023
Background: For patients with atrial fibrillation who have an ischemic stroke or transient ischemic attack (TIA) despite taking direct oral anticoagulants (DOACs), the optimal strategy for ongoing anticoagulation is unknown.
Eric Duong, BSc, MSc, PharmD, Mu Lin, PhD, Mathew Hodgson, BSP, Glen Jickling, MD, MSc, FRCPC, Kirsten George-Phillips, BSP, Tammy J. Bungard, BSP, PharmD   +5 more
doaj   +1 more source

Sudden hemothorax as a rare initial manifestation of bronchiectasis under a direct oral anticoagulant

Surgical Case Reports, 2022
Background A hemothorax as the initial manifestation of bronchiectasis is extremely rare. We report a case of a sudden hemothorax due to exacerbation of clinically latent bronchiectasis under a direct oral anticoagulant.
Hikaru Nakayama, Asuka Uebayashi, Shota Yagi, Shuhei Iizuka, Yoshiro Otsuki, Toru Nakamura   +5 more
doaj   +1 more source

Prevention of ischemic stroke in atrial fibrillation from the point of view of a neurologist. Standards and real clinical practice

Терапевтический архив, 2021
The article outlines aspects of the current state of the problem of the priority choice of an oral anticoagulant for indefinite prevention of stroke and systemic thromboembolism in patients with atrial fibrillation.
Marina Yu. Maksimova, Andrei V. Fonyakin, Liudmila A. Geraskina   +2 more
doaj   +1 more source

Safety of direct oral anticoagulants in patients with atrial fibrillation and high risk of stroke (review of literature)

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2020
Review discusses the problem of non-vitamin K antagonist oral anticoagulants safety in patients with non-valvular atrial fibrillation. Bleeding risk assessment while applying anticoagulant therapy, preventive methods for major bleeding (intracranial ...
E. I. Baranova, V. A. Ionin, A. A. Katsap, O. S. Kolesnik, E. V. Lebedeva   +4 more
doaj   +1 more source

Potential of anticoagulant therapy in cardiology practice for thrombocytopenia. Literature review

Российский кардиологический журнал, 2023
The review article discusses the issues of anticoagulant therapy in cardiovascular patients with thrombocytopenia (TP), gives the concept of ethylenediaminetetraacetic acidand heparin-induced TP.
K. G. Pereverzeva, S. S. Yakushin, A. An. Korshikova   +2 more
doaj   +1 more source