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DIRECT ORAL ANTICOAGULANTS

open access: yesАкушерство, гинекология и репродукция, 2016
Several direct oral anticoagulants (DOACs), namely, apixaban, rivaroxaban, and dabigatran etexilate, are currently licensed in Europe and the United States for various thromboembolic indications.
I. Tzoran, B. Brenner
doaj   +7 more sources

Reversal of direct oral anticoagulants [PDF]

open access: yesVascular Health and Risk Management, 2017
Mosaad Almegren Department of Medicine, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Kingdom of Saudi Arabia Abstract: Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a ...
Almegren M
doaj   +7 more sources

A three-year prospective study of the presentation and clinical outcomes of major bleeding episodes associated with oral anticoagulant use in the UK (ORANGE study) [PDF]

open access: yesHaematologica, 2018
The outcomes of patients developing major bleeding while on oral anticoagulants remain largely unquantified. The objectives of this study were to: (i) describe the burden of major hemorrhage associated with all available oral anticoagulants in terms of ...
Laura Green   +10 more
doaj   +5 more sources

Direct oral anticoagulants and venous thromboembolism [PDF]

open access: yesEuropean Respiratory Review, 2016
Venous thromboembolism (VTE), consisting of deep vein thrombosis and pulmonary embolism, is a major clinical concern associated with significant morbidity and mortality.
Massimo Franchini   +1 more
doaj   +5 more sources

Direct-acting oral anticoagulants: An overview

open access: yesSaudi Journal of Medicine and Medical Sciences, 2017
In today's practice, an increasing number of patients are prescribed anticoagulant therapy. Short-term anticoagulation as a primary or secondary prophylaxis of thrombosis is standard of care in many clinical indications.
Hatem H Salem
doaj   +4 more sources

Overview of the Direct Oral Anticoagulants [PDF]

open access: goldJournal of the Minneapolis Heart Institute Foundation, 2017
ABSTRACT Over the past 6 decades, warfarin has proven efficacious in reducing stroke risk in patients with atrial fibrillation and reducing the risk of recurrent venous thromboembolism in patients with acute deep vein thrombosis or pulmonary embolism.
Nedaa Skeik   +2 more
openalex   +3 more sources

Safety and interaction of direct oral anticoagulants with antiarrhythmic drugs

open access: yesРоссийский кардиологический журнал, 2021
The use of direct oral anticoagulants minimized the risks associated with vitamin K antagonist (warfarin) therapy. Currently, direct oral anticoagulants have priority over warfarin for the prevention of thromboembolic events in patients with atrial ...
B. A. Tatarsky, N. V. Kazyonnova
doaj   +1 more source

Direct oral anticoagulants in antiphospholipid syndrome

open access: yesRevista Brasileira de Reumatologia, 2016
Jozélio Freire de Carvalho   +2 more
doaj   +4 more sources

Direct oral anticoagulants uptake and an oral anticoagulation paradox [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2020
Oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation is underutilised. One of the impediments to warfarin therapy is the frequent monitoring required, usually at a specialised warfarin clinic. The advent of direct oral anticoagulants (DOACs) facilitates OAC therapy without an onerous monitoring regimen. This benefit may
Cormac Kennedy   +4 more
openaire   +3 more sources

Thrombocytopenia Induced by Direct Oral Anticoagulants: a Clinical Case and Literature Review

open access: yesРациональная фармакотерапия в кардиологии, 2022
The last decade has dramatically changed the strategy of anticoagulant therapy in patients with atrial fibrillation. Direct oral anticoagulants have replaced vitamin K antagonists: either direct thrombin blockers (dabigatran) or factor IIa blockers ...
B. A. Tatarsky, N. V. Kazennova
doaj   +1 more source

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