Results 11 to 20 of about 64,446 (303)

DIRECT ORAL ANTICOAGULANTS

open access: yesАкушерство, гинекология и репродукция, 2016
Several direct oral anticoagulants (DOACs), namely, apixaban, rivaroxaban, and dabigatran etexilate, are currently licensed in Europe and the United States for various thromboembolic indications.
I. Tzoran, B. Brenner
doaj   +4 more sources

A three-year prospective study of the presentation and clinical outcomes of major bleeding episodes associated with oral anticoagulant use in the UK (ORANGE study) [PDF]

open access: yesHaematologica, 2018
The outcomes of patients developing major bleeding while on oral anticoagulants remain largely unquantified. The objectives of this study were to: (i) describe the burden of major hemorrhage associated with all available oral anticoagulants in terms of ...
Laura Green   +10 more
doaj   +5 more sources

Reversal of direct oral anticoagulants

open access: yesVascular Health and Risk Management, 2017
Mosaad Almegren Department of Medicine, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Kingdom of Saudi Arabia Abstract: Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a ...
Almegren M
doaj   +6 more sources

Direct-acting oral anticoagulants: An overview

open access: yesSaudi Journal of Medicine and Medical Sciences, 2017
In today's practice, an increasing number of patients are prescribed anticoagulant therapy. Short-term anticoagulation as a primary or secondary prophylaxis of thrombosis is standard of care in many clinical indications.
Hatem H Salem
doaj   +3 more sources

Safety and interaction of direct oral anticoagulants with antiarrhythmic drugs

open access: yesРоссийский кардиологический журнал, 2021
The use of direct oral anticoagulants minimized the risks associated with vitamin K antagonist (warfarin) therapy. Currently, direct oral anticoagulants have priority over warfarin for the prevention of thromboembolic events in patients with atrial ...
B. A. Tatarsky, N. V. Kazyonnova
doaj   +1 more source

Thrombocytopenia Induced by Direct Oral Anticoagulants: a Clinical Case and Literature Review

open access: yesРациональная фармакотерапия в кардиологии, 2022
The last decade has dramatically changed the strategy of anticoagulant therapy in patients with atrial fibrillation. Direct oral anticoagulants have replaced vitamin K antagonists: either direct thrombin blockers (dabigatran) or factor IIa blockers ...
B. A. Tatarsky, N. V. Kazennova
doaj   +1 more source

Effectiveness and safety of oral anticoagulants for non-valvular atrial fibrillation: a population-based cohort study in primary healthcare in Catalonia

open access: yesFrontiers in Pharmacology, 2023
Objectives: Our objective was to analyse effectiveness and safety of oral anticoagulants (OAC) for stroke prevention in non-valvular atrial fibrillation.Material and methods: Population-based cohort study including adults initiating oral anticoagulants ...
Maria Giner-Soriano   +18 more
doaj   +1 more source

Direct oral anticoagulants (DOACs) [PDF]

open access: yesVascular Medicine, 2015
DOACs are a new group of blood-thinner medications that may have some advantages over warfarin. A health care provider will look at several different factors to help patients decide if a DOAC is a good choice. Patients taking DOACs should discuss medication changes, a plan for taking the DOAC before and after a surgery, and any bleeding side effects ...
Sara, Vazquez, Matthew T, Rondina
openaire   +2 more sources

Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Renal Dysfunction

open access: yesРациональная фармакотерапия в кардиологии, 2021
Atrial fibrillation and renal dysfunction often coexist, each disorder may predispose to the other and contribute to worsening prognosis. Both atrial fibrillation and chronic kidney disease are associated with increased risk of stroke and thromboembolic ...
Z. D. Kobalava   +2 more
doaj   +1 more source

Direct oral anticoagulants uptake and an oral anticoagulation paradox [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2020
Oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation is underutilised. One of the impediments to warfarin therapy is the frequent monitoring required, usually at a specialised warfarin clinic. The advent of direct oral anticoagulants (DOACs) facilitates OAC therapy without an onerous monitoring regimen. This benefit may
Cormac Kennedy   +4 more
openaire   +2 more sources

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