Results 41 to 50 of about 67,152 (253)

Laboratory measurement of the direct oral anticoagulants [PDF]

open access: yesBritish Journal of Haematology, 2015
SummaryDirect oral anticoagulants (DOACs), including the direct thrombin inhibitor, dabigatran, and the direct factor Xa (FXa) inhibitors, rivaroxaban, apixaban and edoxaban, are approved for thromboembolism prevention and treatment. These drugs do not require routine coagulation monitoring but, in some circumstances, measurement of drug level or ...
Noel C. Chan   +3 more
openaire   +3 more sources

Systematic errors in the choice of dose level of direct oral anticoagulants: urgency of an issue and approaches to its solution

open access: yesМедицинский совет, 2021
The article presents updated information on the frequency of use of non-recommended low dosing of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban).
S. R. Gilyarevskiy   +3 more
doaj   +1 more source

XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation. [PDF]

open access: yes, 2014
Atrial fibrillation (AF) is associated with a fivefold increase in the risk of stroke. The Phase III ROCKET AF (Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in ...
Amarenco, P   +6 more
core   +2 more sources

Laboratory Monitoring of Direct Oral Anticoagulants (DOACs)

open access: yesBiomedicines, 2021
The introduction of direct oral anticoagulants (DOACs), such as dabigatran, rivaroxaban, apixaban, edoxaban, and betrixaban, provides safe and effective alternative to previous anticoagulant therapies.
Claire Dunois
doaj   +1 more source

The relationships between vitamin K and cognition: a review of current evidence [PDF]

open access: yes, 2019
Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico   +7 more
core   +2 more sources

Monitoring and reversal of direct oral anticoagulants [PDF]

open access: yesHematology, 2015
AbstractAlthough the direct oral anticoagulants (DOACs) do not require routine monitoring and reduce bleeding compared with warfarin, there are special circumstances in which laboratory measurement or reversal of their anticoagulant effect may be indicated.
Deborah M. Siegal, Adam Cuker
openaire   +2 more sources

Rivaroxaban Treatment for Heparin-Induced Thrombocytopenia: A Case Report and a Review of the Current Experience

open access: yesCase Reports in Hematology, 2020
Heparin-induced thrombocytopenia is a life-threatening complication of exposure to heparin. Heparin-induced thrombocytopenia results from an autoantibody directed against platelet factor 4 in complex with heparin.
Mohamed Aon, Omar Al-Shammari
doaj   +1 more source

Direct-acting oral anticoagulants in antiphospholipid syndrome

open access: yesНаучно-практическая ревматология, 2021
Antiphospholipid syndrome is an acquired autoimmune thrombophilia characterized by the development of recurrent vascular thrombosis of any caliber and type or obstetric pathology and the mandatory identification of persistently positive antiphospholipid ...
T. M. Reshetnyak, K. S. Nurbaeva
doaj   +1 more source

Are direct oral anticoagulants preferable to warfarin for the treatment of left ventricular thrombi? A Bayesian meta-analysis of randomized controlled trials

open access: yesAmerican Heart Journal Plus, 2021
Background: There is no clear consensus on the optimal choice of anticoagulant in patients with left ventricular thrombi (LVT). Given the potentially fatal complications associated with this disease entity, we performed a systematic review and meta ...
Ahmed Sayed   +5 more
doaj   +1 more source

Threats to safe transitions from hospital to home: a consensus study in North West London primary care. [PDF]

open access: yes, 2019
BACKGROUND: Transitions between healthcare settings are vulnerable points for patients. AIM: To identify key threats to safe patient transitions from hospital to primary care settings.
Ashrafian, H.   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy