Results 61 to 70 of about 784,362 (267)
Comparing variable neighbourhood search algorithms for the direct aperture optimisation in radiotherapy [PDF]
PeerJ Computer ScienceIntensity modulated radiation therapy (IMRT) is a prevalent approach for administering radiation therapy in cancer treatment. The primary objective of IMRT is to devise a treatment strategy that eradicates cancer cells from the tumour while minimising ...
Mauricio Moyano +5 more
doaj +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Practical, Robust and Fast Method for Location Localization in Range-Based Systems
Sensors, 2017 Location localization technology is used in a number of industrial and civil applications. Real time location localization accuracy is highly dependent on the quality of the distance measurements and efficiency of solving the localization equations.
Shiping Huang, Zhifeng Wu, Anil Misra
doaj +1 more source
The search for directed intelligence [PDF]
REACH, 2016 We propose a search for sources of directed energy systems such as those now becoming technologically feasible on Earth. Recent advances in our own abilities allow us to foresee our own capability that will radically change our ability to broadcast our presence.
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Optimal frequency regulation in an uncertain islanded microgrid: A modified direct search algorithm
IET Renewable Power Generation, 2022 This paper presents a methodology for frequency regulation in a microgrid involving renewable energy sources (RES) using a dynamic controller, which is an output feedback controller (OFC).
Roozbeh Abolpour +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Correction: Transcranial direct current stimulation (tDCS) facilitates overall visual search response times but does not interact with visual search task factors. [PDF]
PLoS ONE, 2018 [This corrects the article DOI: 10.1371/journal.pone.0194640.].
Kyongje Sung, Barry Gordon
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source