Results 71 to 80 of about 891,818 (308)

Challenges for dark matter direct search with SiPMs

open access: yesFrontiers in Physics
Liquid xenon and liquid argon detectors are leading the direct dark matter search and are expected to be the candidate technology for the forthcoming generation of ultra-sensitive large-mass detectors.
Alessandro Razeto, Nicola Rossi
doaj   +1 more source

Optimization of Transformation Coefficients Using Direct Search and Swarm Intelligence [PDF]

open access: yesProblems of the Regional Energetics, 2017
This research considers optimization of tap position of transformers in power systems to reduce power losses. Now, methods based on heuristic rules and fuzzy logic, or methods that optimize parts of the whole system separately, are applied to this ...
Manusov V.Z., Matrenin P.V., Orlov D.V.
doaj  

Strategies to optimize MEDLINE and EMBASE search strategies for anesthesiology systematic reviews. An experimental study

open access: yesSão Paulo Medical Journal, 2018
BACKGROUND: A high-quality electronic search is essential for ensuring accuracy and comprehensiveness among the records retrieved when conducting systematic reviews. Therefore, we aimed to identify the most efficient method for searching in both MEDLINE
Enilze de Souza Nogueira Volpato   +9 more
doaj   +1 more source

Search Computing Challenges and Directions [PDF]

open access: yes, 2010
Search Computing (SeCo) is a project funded by the European Research Council (ERC). It focuses on building the answers to complex search queries like "Where can I attend an interesting conference in my field close to a sunny beach?" by interacting with a constellation of cooperating search services, using ranking and joining of results as the dominant ...
CERI, STEFANO   +4 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Comparing variable neighbourhood search algorithms for the direct aperture optimisation in radiotherapy [PDF]

open access: yesPeerJ Computer Science
Intensity modulated radiation therapy (IMRT) is a prevalent approach for administering radiation therapy in cancer treatment. The primary objective of IMRT is to devise a treatment strategy that eradicates cancer cells from the tumour while minimising ...
Mauricio Moyano   +5 more
doaj   +2 more sources

Greedoids and searches in directed graphs

open access: yesDiscrete Mathematics, 1991
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Directed search, unemployment and public policy [PDF]

open access: yesCanadian Journal of Economics/Revue canadienne d'économique, 2009
Abstract We examine the effects of public policy parameters in a simple directed search model of the labour market, and contrast them with those in standard random matching models with Nash bargaining. Both finite and limit versions of the directed search model are considered, and the value of the limit model as an approximation of the finite one is ...
Kennes, John   +3 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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