Results 61 to 70 of about 891,818 (308)
A model of directed consumer search [PDF]
Peer ...
Haan, Marco A. +2 more
openaire +3 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Inflation, price competition and consumer search technology [PDF]
This paper studies an (S, s) pricing model from the perspective of inflation and price competition in search markets. I present a model in which consumers'search technologies can influence firms' price setting, price dispersion, and the market structure.
Watanabe Watanabe, Makoto +1 more
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Optimisation of dynamic reactive power sources using mesh adaptive direct search
Dynamic reactive power sources can be used to effectively mitigate the fault‐induced delayed voltage recovery and transient voltage instability issues.
Weihong Huang +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Direction-optimizing Breadth-First Search [PDF]
Breadth-First Search is an important kernel used by many graph-processing applications. In many of these emerging applications of BFS, such as analyzing social networks, the input graphs are low-diameter and scale-free. We propose a hybrid approach that is advantageous for low-diameter graphs, which combines a conventional top-down algorithm along with
Scott Beamer +2 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Direct Search in Conceptual Design
The notion Concept implies a set of rules and ideas combining in a common intention actual principles for application, structure and form of a future artificial object.
E. B. Skvortsov
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

