Results 111 to 120 of about 270,748 (303)

Progress in the study of functional genes related to direct seeding of rice. [PDF]

Mol Breed, 2023
Li X, Dong J, Zhu W, Zhao J, Zhou L.
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Preliminary Study on Optimizing Rice Production in Cold Regions: Yield and Nutritional Trade-Offs Between Transplanting and Mechanical Hill-Drop Seeding

Agronomy
Direct seeding of rice reduces labor intensity and cost, helping alleviate labor shortages in cold-region rice production. To investigate the effects of mechanical precision hill-direct seeding versus mechanical transplanting on yield and nutrient ...
Huaguo Ding, Songjin Zhou, Jiabao Han, Yingying Liu, Ziliang Cao, Lei Lei, Mingliang Bai, Yu Luo, Guang Yang, Lei Chen, Kai Liu, Wu-Rina Sun, Pinglian Sun, Chenshi Sun   +13 more
doaj   +1 more source

Structure-based inhibitors of amyloid beta core suggest a common interface with tau. [PDF]

, 2019
Alzheimer's disease (AD) pathology is characterized by plaques of amyloid beta (Aβ) and neurofibrillary tangles of tau. Aβ aggregation is thought to occur at early stages of the disease, and ultimately gives way to the formation of tau tangles which ...
Bowler, Jeannette, Cascio, Duilio, Eisenberg, David S, Glabe, Charles G, Gonen, Tamir, Griner, Sarah L, Murray, Kevin A, Philipp, Stephan, Rodriguez, Jose A, Sahay, Shruti, Sawaya, Michael R, Seidler, Paul, Sosna, Justyna, Yang, Tianxiao Peter   +13 more
core   +1 more source

Direct seeded rice

, 2022
Anjani Kumar, Amaresh Kumar Nayak, Mehreteab Tesfai, Rahul Tripathi, Sangita Mohanty, Shyamaranjan Das Mohapatra, Kiran Mohapatra, Udaya Sekhar Nagothu   +7 more
openaire   +1 more source

Effects of Low Light after Heading on the Yield of Direct Seeding Rice and Its Physiological Response Mechanism. [PDF]

Plants (Basel), 2023
Ma P, Zhou L, Liao XH, Zhang KY, Aer LS, Yang EL, Deng J, Zhang RP.   +7 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Effect of Sowing Date on the Growth Characteristics and Yield of Growth-Constrained Direct-Seeding Rice. [PDF]

Plants (Basel), 2023
Zhang RP, Zhou NN, Ashen RG, Zhou L, Feng TY, Zhang KY, Liao XH, Aer LS, Shu JC, He XW, Gao F, Ma P.   +11 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source